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. 2022 Jan 14;3(1):1-2.
doi: 10.1016/j.medj.2021.12.006.

Harnessing defective viruses to fight infections

Sébastien A Felt  1 , Carolina B López  2
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Harnessing defective viruses to fight infections

Sébastien A Felt et al. Med. .
Free article

Abstract

One of the most pressing challenges in medicine is to develop fast and effective strategies to combat infections. Xiao et al.1 report proof-of-concept experiments for the use of defective viral genomes as broad-spectrum antivirals by harnessing their ability to stimulate the innate immune response.

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Conflict of interest statement

Declaration of interests C.B.L. has a related patent: Methods and Compositions for Stimulating Immune Response Using Potent Immunostimulatory RNA Motifs, patent number 10,624,964, granted on April 21, 2020. The priority date for the patent is May 1, 2015.

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