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Comment
. 2022 Mar 11;3(3):159-161.
doi: 10.1016/j.medj.2022.02.005.

Targeting Epstein-Barr virus to treat MS

Tanuja Chitnis  1 , Howard L Weiner  2
Affiliations
Free article
Comment

Targeting Epstein-Barr virus to treat MS

Tanuja Chitnis et al. Med. .
Free article

Abstract

Epstein-Barr virus (EBV) is a putative trigger for multiple sclerosis (MS). Bjornevik et al. utilized longitudinal analysis of 10 million adults to strongly link MS to EBV infection1 and Lanz et al. identified clonally expanded B cells in MS that bind EBV EBNA1 and GlialCam.2.

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Conflict of interest statement

Declaration of interests The authors declare no competing interests.

Comment on

  • Clonally expanded B cells in multiple sclerosis bind EBV EBNA1 and GlialCAM.
    Lanz TV, Brewer RC, Ho PP, Moon JS, Jude KM, Fernandez D, Fernandes RA, Gomez AM, Nadj GS, Bartley CM, Schubert RD, Hawes IA, Vazquez SE, Iyer M, Zuchero JB, Teegen B, Dunn JE, Lock CB, Kipp LB, Cotham VC, Ueberheide BM, Aftab BT, Anderson MS, DeRisi JL, Wilson MR, Bashford-Rogers RJM, Platten M, Garcia KC, Steinman L, Robinson WH. Lanz TV, et al. Nature. 2022 Mar;603(7900):321-327. doi: 10.1038/s41586-022-04432-7. Epub 2022 Jan 24. Nature. 2022. PMID: 35073561 Free PMC article.

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