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Comment
. 2021 Jul 9;2(7):794-796.
doi: 10.1016/j.medj.2021.06.008.

Finding a sweet spot for leptin

Rebecca J Brown  1 , Marc L Reitman  2
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Finding a sweet spot for leptin

Rebecca J Brown et al. Med. .
Free article

Abstract

Non-alcoholic fatty liver disease (NAFLD) is a growing public health problem that progresses to serious liver disease in some patients and for which there are no FDA-approved therapies. In this issue of Med, Akinci et al.1 present encouraging preliminary data showing that treatment with recombinant leptin has beneficial effects on NAFLD.

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Conflict of interest statement

Declaration of interests R.J.B. has received in-kind research support (donation of metreleptin for investigator-initiated studies) from Amgen, Amylin Pharmaceuticals, Bristol Myers Squibb/Astra Zeneca, Aegerion Pharmaceuticals, and Amryt Pharma, and serves in an unpaid advisory capacity for Amryt Pharma. M.L.R. declares no competing interest.

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