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Review
. 2022 Apr;45(2):53-57.
doi: 10.18773/austprescr.2022.006. Epub 2022 Apr 1.

Troponins in myocardial infarction and injury

Julia M Potter  1   2   3 , Peter E Hickman  1   2   3 , Louise Cullen  1   2   3
Affiliations
Review

Troponins in myocardial infarction and injury

Julia M Potter et al. Aust Prescr. 2022 Apr.

Abstract

Troponins are proteins that are integral components of the contractile mechanism of muscle, including cardiac muscle. Cardiac troponins Iand T can be detected in the blood of most people after puberty, at concentrations reflecting cardiac mass, sex and age. Current laboratory assays are approximately 1000 times more sensitive than those used previously. They also have higher sensitivity than point-of-care assays. The measurement of cardiac troponins is used primarily to assist in the diagnosis or exclusion of myocardial injury. Serial tests in acute coronary syndrome are guided by the Universal Definition of Myocardial Infarction.

Keywords: acute coronary syndromes; cardiac troponins; myocardial infarction; point-of-care testing.

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Conflict of interest statement

Conflicts of interest: none declared

Figures

Fig.1
Fig.1
Cardiac muscle
Fig. 2
Fig. 2
Troponin concentration–time curves
See this image and copyright information in PMC

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