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Review
. 2022 Jun;49(2):315-326.
doi: 10.1016/j.pop.2021.11.010. Epub 2022 Apr 22.

Pharmacology: Non-Insulin Agents

Heather O'Brien  1 , Catherine Travis  2
Affiliations
Review

Pharmacology: Non-Insulin Agents

Heather O'Brien et al. Prim Care. 2022 Jun.

Abstract

The landscape of diabetes treatment has evolved significantly in recent years. While metformin remains first-line for the treatment of type 2 diabetes, 2 new classes of medications (sodium-glucose cotransporter 2 inhibitors and glucagon-like peptide agonists) are becoming mainstays in therapy. These classes boast strong efficacy and desired long-term outcomes, offering cardiovascular and renal protection, as well as other benefits such as weight loss and low risk of hypoglycemia. Most recent guidelines have highlighted the importance of using shared decision making and patient-centered choices when determining medication outcomes.

Keywords: Diabetes pharmacology; Diabetes treatment; Non-insulin; Type 2 diabetes.

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Conflict of interest statement

Disclosure The authors have nothing to disclose. Neither author has commercial or financial conflicts of interest.

MeSH terms