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Randomized Controlled Trial
. 2022 Nov;54(11):2977-2981.
doi: 10.1007/s11255-022-03218-0. Epub 2022 May 21.

A prospective randomized controlled trial comparing the effect and safety of Piranha and VersaCut morcellation devices in transurethral holmium laser enucleation of the prostate

Yanbo Chen #  1 , Huan Xu #  1 , Dajun Gao #  1 , Meng Gu  1 , Chong Liu  1 , Ming Zhan  1 , Zhikang Cai  1 , Qi Chen  2 , Zhong Wang  3
Affiliations
Randomized Controlled Trial

A prospective randomized controlled trial comparing the effect and safety of Piranha and VersaCut morcellation devices in transurethral holmium laser enucleation of the prostate

Yanbo Chen et al. Int Urol Nephrol. 2022 Nov.

Abstract

Purpose: Holmium laser enucleation of the prostate (HoLEP) is reported to be widely used in the surgical treatment of benign prostatic hyperplasia (BPH), which consists of two procedures: enucleation and morcellation. This study is to examine the efficiency and safety of two different morcellator systems within a cohort of men undergoing HoLEP for BPH.

Methods: A total of 210 consecutive patients undergoing HoLEP and morcellation procedures were enrolled. Individuals were randomly divided into 2 separated groups: the first group (105 patients) was performed with a nephroscope using a mechanical Versacut morcellator and the second (105 patients) was performed with the new morcellation system, nephroscopes and Piranha morcellator. Perioperative characteristics were studied and analyzed.

Results: The morcellation time and the morcellation rate was similar when the prostate volume (PV) ≤ 60 mL while the morcellation time was significantly shorter and the morcellation rate was higher in the Piranha group with PV > 60 mL. No significant difference was observed according to the bladder irrigation time, indwelling catheter time, and discharge time.

Conclusion: Piranha morcellator presents a higher efficiency for the prostate over 60 mL.

Keywords: Benign prostatic hyperplasia; Holmium laser enucleation of the prostate; Morcellation; Randomized controlled trial.

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