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Review
. 2023 Jun;49(6):1061-1067.
doi: 10.1016/j.ejso.2022.05.010. Epub 2022 May 16.

Histology-tailored multidisciplinary management of primary retroperitoneal sarcomas

S Bonvalot  1 , C Roland  2 , C Raut  3 , C Le Péchoux  4 , D Tzanis  5 , A M Frezza  6 , A Gronchi  7
Affiliations
Review

Histology-tailored multidisciplinary management of primary retroperitoneal sarcomas

S Bonvalot et al. Eur J Surg Oncol. 2023 Jun.

Abstract

Until recently, the recommendation for primary retroperitoneal sarcomas (RPS) was to perform a complete en-bloc gross excision, (neo) adjuvant treatments being options which were not validated by randomized studies, with a large discrepancy of use between centers. The heterogeneity of RPS, with their different biological behaviour, renders a homogenous therapeutic and surgical approach probably inappropriate. Recent studies, both surgical and dedicated to adjuvant treatments, allow refining these recommendations. This review summarizes recent advances and directions.

Keywords: Chemotherapy; Diagnosis; Liposarcoma; Radiotherapy; Retroperitoneal sarcoma; Retroperitoneal tumour; Solitary fibrous Tumor; Surgery; leiomyosarcoma.

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Conflict of interest statement

Declaration of competing interest The authors have no potential conflicts of interest to disclose.