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. 2023 Jan;44(1):149-151.
doi: 10.1017/ice.2022.79. Epub 2022 May 23.

Coronavirus disease 2019 (COVID-19) hospitalization metrics that do not account for disease severity underestimate protection provided by severe acute respiratory coronavirus virus 2 (SARS-CoV-2) vaccination and boosting: A retrospective cohort study

June K Corrigan #  1 , Jennifer La #  1 , Nathanael R Fillmore  1   2   3   4 , Nhan V Do  1   2   5 , Mary Brophy  1   2   5 , Shira Doron  6 , Paul A Monach #  1   2   4 , Westyn Branch-Elliman #  2   4   7
Affiliations

Coronavirus disease 2019 (COVID-19) hospitalization metrics that do not account for disease severity underestimate protection provided by severe acute respiratory coronavirus virus 2 (SARS-CoV-2) vaccination and boosting: A retrospective cohort study

June K Corrigan et al. Infect Control Hosp Epidemiol. 2023 Jan.
No abstract available

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Figures

Fig. 1.
Fig. 1.
Trends in metrics of severity of SARS-CoV-2 infection over time in patients hospitalized contemporaneous with a positive test, stratified by vaccination status (unvaccinated, vaccinated but not boosted, or boosted). The period of predominance of the SARS-CoV-2 δ (delta) variant was approximately July 1, 2021, to November 30, 2021, and that of the SARS-CoV-2 (omicron) variant beginning December 1, 2021. (A) Minimum oxygen saturation (SpO2) < 94% or supplementary oxygen at any level (cf, minimum used is ≥0.5 L/minute). (B) Minimum SpO2 < 90% or supplementary oxygen ≥2 L/minute. (C) Use of dexamethasone during hospitalization. (D) Use of remdesivir during hospitalization.
See this image and copyright information in PMC

References

    1. Fillmore NR, La J, Zheng C, et al. The COVID-19 hospitalization metric in the pre- and post-vaccination eras as a measure of pandemic severity: a retrospective, nationwide cohort study. Infect Control Hosp Epidemiol 2021. doi: 10.1017/ice.2022.13. - DOI - PMC - PubMed
    1. Fast HE, Zell E, Murthy BP, et al. Booster and additional primary dose COVID-19 vaccinations among adults aged ≥65 years—United States, August 13, 2021–November 19, 2021. Morb Mortal Wkly Rep 2021;70:1735. - PMC - PubMed
    1. Interim clinical considerations for use of COVID-19 vaccines currently authorized in the United States. Centers for Disease Control and Prevention website. https://www.cdc.gov/vaccines/covid-19/clinical-considerations/covid-19-v.... Update April 21, 2022. Accessed May 17, 2022.
    1. COVID-19 shared data resource. US Department of Veterans’ Affairs website. https://www.hsrd.research.va.gov/for_researchers/cyber_seminars/archives.... Published 2020. Accessed May 17, 2022.
    1. Guidebook on COVID-19 Testing v1.2 27 (2021). US Department of Veterans Affairs (Internal Guidance and Recommendations)..

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