Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2022 May 12:10:20503121221096602.
doi: 10.1177/20503121221096602. eCollection 2022.

Post-discharge follow-up of patients with COVID-19: A Brazilian experience

Affiliations

Post-discharge follow-up of patients with COVID-19: A Brazilian experience

Luis Filipe Nakayama et al. SAGE Open Med. .

Abstract

Objective: The objective of this study is to evaluate post-acute symptoms in patients with confirmed severe and critical coronavirus disease 2019 infections.

Methods: We evaluated patients with confirmed severe and critical coronavirus disease 2019 infections. Post-acute symptoms were defined as symptoms persisting 4 weeks after the onset of the symptoms and classified as pulmonary, muscular, hematologic, neuropsychiatric, renal, and dermatological.

Results: We recovered data from 565 patients (43.7% female) with a mean age of 61.1 years. In 18.2%, at least one hospital readmission was necessary and 11.1% died. In 62.6%, there was at least one persistent symptom, and 28.8% had more than one. Among associated factors, obesity, intensive care support, and mechanical ventilation were related to persistent symptoms.

Conclusion: The most prevalent symptoms were pulmonary and neuropsychiatric sequelae, as reported in previous studies. This finding underscores the severity of the coronavirus disease 2019 infection and the need for follow-up after recovery from the initial illness. Obese patients, those requiring mechanical ventilation, female patients, and increased hospital length are at greater chance of having persistent symptoms.

Keywords: COVID-19; SARS-CoV-2; coronavirus; post-COVID; post-COVID syndrome.

PubMed Disclaimer

Conflict of interest statement

Declaration of conflicting interests: The author(s) declared no potential conflicts of interest with respect to the research, authorship, and/or publication of this article.

Figures

Figure 1.
Figure 1.
Flowchart of patients’ selection: total patient admission, hospital discharge, deaths, missing contact, and enrolled patients.

References

    1. Samudrala PK, Kumar P, Choudhary K, et al.. Virology, pathogenesis, diagnosis and in-line treatment of COVID-19. Eur J Pharmacol 2020; 883: 173375. - PMC - PubMed
    1. Wu Z, McGoogan JM. Characteristics of and important lessons from the coronavirus disease 2019 (COVID-19) outbreak in China: summary of a report of 72 314 cases from the Chinese Center for Disease Control and Prevention. JAMA 2020; 323: 1239–1242. - PubMed
    1. Nalbandian A, Sehgal K, Gupta A, et al.. Post-acute COVID-19 syndrome. Nat Med 2021; 27: 601–615. - PMC - PubMed
    1. Schou TM, Joca S, Wegener G, et al.. Psychiatric and neuropsychiatric sequelae of COVID-19—a systematic review. Brain Behav Immun 2021; 97: 328–348. - PMC - PubMed
    1. Likhvantsev V, Landoni G, Perekhodov S, et al.. Six-month quality of life in COVID-19 intensive care unit survivors. J Cardiothorac Vasc Anesth. Epub ahead of print 28 August 2021. DOI: 10.1053/j.jvca.2021.08.036. - DOI - PMC - PubMed

LinkOut - more resources