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Review
. 2021 Jul 20;26(2):e281-e288.
doi: 10.1055/s-0041-1726041. eCollection 2022 Apr.

Auditory and Vestibular Functioning in Individuals with Type-2 Diabetes Mellitus: A Systematic Review

Prawin Kumar  1 , Niraj Kumar Singh  1 , Kumari Apeksha  2 , Vipin Ghosh  2 , Raveendran Rajesh Kumar  2 , Bhanu Kumar Muthaiah  3
Affiliations
Review

Auditory and Vestibular Functioning in Individuals with Type-2 Diabetes Mellitus: A Systematic Review

Prawin Kumar et al. Int Arch Otorhinolaryngol. .

Abstract

Introduction Diabetes mellitus is a metabolic disease associated with a rise in the level of blood glucose. Individuals with diabetes mellitus are more likely to develop hearing loss, tinnitus, and dizziness due to macro- and microvascular complications. The extent to which auditory and vestibular functions are impaired in individuals with type-2 diabetes mellitus is still under debate. Objective To systematically review studies focusing on auditory and vestibular functions in individuals with type-2 diabetes mellitus. Data Synthesis A search was conducted in the PubMed, MedlinePlus, Ingenta Connect and Google Scholar databases for articles published until June 2019. A total of 15,980 articles were primarily retrieved, 33 of which were shortlisted based on the inclusion criteria set by the investigators for the systematic review. Out of 33 full-length articles, 26 evaluated the functioning of the auditory system, while 7 evaluated the functioning of the vestibular system. Most studies related to auditory functioning reported a significant effect of type-2 diabetes mellitus on the peripheral auditory system, whereas studies on vestibular functioning reported no significant effect of diabetes mellitus on the functioning of the peripheral vestibular end-organ. Conclusion Overall, the results of various audiological and peripheral vestibular tests reveal distinctive peripheral and/or central auditory and vestibular end-organ impairments in individuals with type-2 diabetes mellitus.

Keywords: cochlea; diabetes mellitus; hearing loss; inner ear; vertigo.

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Conflict of interest statement

Conflict of Interests The authors have no conflict of interests to declare.

Figures

Fig. 1
Fig. 1
PRISMA flowchart of the literature review process.
See this image and copyright information in PMC

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