Investing in Late-Life Brain Capital

Walter D Dawson¹, Erin Smith², Laura Booi², Maia Mosse³, Helen Lavretsky⁴, Charles F Reynolds 3rd⁵, Jeffrey Cummings⁶, Patrick Brannally⁷, William Hynes³, Eric J Lenze⁸, Facundo Manes⁹, Rym Ayadi¹⁰, Lori Frank¹¹, Sandra Bond Chapman¹², Ian H Robertson², Lori Rubenstein¹³, Jorge Jraissati¹⁴, Agustin Ibáñez², Howard Fillit¹⁵, Dilip V Jeste¹⁶, Anitha Rao¹⁷, Michael Berk¹⁸, Eric A Storch¹⁹, Antonella Santuccione Chadha²⁰, Harris A Eyre¹⁸

Affiliations

¹ Department of Neurology, School of Medicine, Oregon Health & Science University, Portland, Oregon, USA.
² Global Brain Health Institute at University of California, San Francisco (UCSF), San Francisco, California, USA.
³ Department of Medicine, Stanford Hospital, Stanford, California, USA.
⁴ Semel Institute for Neuroscience and Human Behavior, University of California, Los Angeles (UCLA), Los Angeles, California, USA.
⁵ Department of Psychiatry, University of Pittsburgh, Pittsburgh, Pennsylvania, USA.
⁶ Chambers-Grundy Center for Transformative Neuroscience, Department of Brain Health, School of Integrated Health Sciences, University of Nevada, Las Vegas, Las Vegas, Nevada, USA.
⁷ Alzheimer's Disease Data Initiative, Gates Ventures, Redwood City, California, USA.
⁸ Department of Psychiatry, Washington University School of Medicine, St Louis, Missouri, USA.
⁹ Institute of Cognitive and Translational Neuroscience (INCYT), INECO Foundation, Favaloro University, Buenos Aires, Argentina.
¹⁰ Euro-Mediterranean Economists Association, Barcelona, Spain.
¹¹ RAND Corporation, Arlington, Virginia, USA.
¹² Center for BrainHealth®, The University of Texas at Dallas, Dallas, Texas, USA.
¹³ Australian Research Alliance for Children and Youth (ARACY), Canberra, Australian Capital Territory, Australia.
¹⁴ IESE Center for Public Leadership and Government, IESE Business School, Madrid, Spain.
¹⁵ Alzheimer's Drug Discovery Foundation (ADDF), New York City, New York, USA.
¹⁶ Departments of Psychiatry and Neurosciences, University of California San Diego, La Jolla, California, USA.
¹⁷ Neurocern, Chicago, Illinois, USA.
¹⁸ IMPACT, the Institute for Mental and Physical Health and Clinical Translation, Deakin University, Geelong, Victoria, Australia.
¹⁹ Department of Psychiatry and Behavioral Sciences, Baylor College of Medicine, Houston, Texas, USA.
²⁰ Biogen, Cambridge, Massachusetts, USA.

PMID: 35602311
PMCID: PMC9116879
DOI: 10.1093/geroni/igac016

Investing in Late-Life Brain Capital

Walter D Dawson et al. Innov Aging. 2022.

. 2022 May 18;6(3):igac016.

doi: 10.1093/geroni/igac016. eCollection 2022.

Authors

Affiliations

¹ Department of Neurology, School of Medicine, Oregon Health & Science University, Portland, Oregon, USA.
² Global Brain Health Institute at University of California, San Francisco (UCSF), San Francisco, California, USA.
³ Department of Medicine, Stanford Hospital, Stanford, California, USA.
⁴ Semel Institute for Neuroscience and Human Behavior, University of California, Los Angeles (UCLA), Los Angeles, California, USA.
⁵ Department of Psychiatry, University of Pittsburgh, Pittsburgh, Pennsylvania, USA.
⁶ Chambers-Grundy Center for Transformative Neuroscience, Department of Brain Health, School of Integrated Health Sciences, University of Nevada, Las Vegas, Las Vegas, Nevada, USA.
⁷ Alzheimer's Disease Data Initiative, Gates Ventures, Redwood City, California, USA.
⁸ Department of Psychiatry, Washington University School of Medicine, St Louis, Missouri, USA.
⁹ Institute of Cognitive and Translational Neuroscience (INCYT), INECO Foundation, Favaloro University, Buenos Aires, Argentina.
¹⁰ Euro-Mediterranean Economists Association, Barcelona, Spain.
¹¹ RAND Corporation, Arlington, Virginia, USA.
¹² Center for BrainHealth®, The University of Texas at Dallas, Dallas, Texas, USA.
¹³ Australian Research Alliance for Children and Youth (ARACY), Canberra, Australian Capital Territory, Australia.
¹⁴ IESE Center for Public Leadership and Government, IESE Business School, Madrid, Spain.
¹⁵ Alzheimer's Drug Discovery Foundation (ADDF), New York City, New York, USA.
¹⁶ Departments of Psychiatry and Neurosciences, University of California San Diego, La Jolla, California, USA.
¹⁷ Neurocern, Chicago, Illinois, USA.
¹⁸ IMPACT, the Institute for Mental and Physical Health and Clinical Translation, Deakin University, Geelong, Victoria, Australia.
¹⁹ Department of Psychiatry and Behavioral Sciences, Baylor College of Medicine, Houston, Texas, USA.
²⁰ Biogen, Cambridge, Massachusetts, USA.

PMID: 35602311
PMCID: PMC9116879
DOI: 10.1093/geroni/igac016

Erratum in

Correction to: Investing in Late-Life Brain Capital.
[No authors listed] [No authors listed] Innov Aging. 2022 Jun 24;6(3):igac042. doi: 10.1093/geroni/igac042. eCollection 2022. Innov Aging. 2022. PMID: 35769167 Free PMC article.

Abstract

Within many societies and cultures around the world, older adults are too often undervalued and underappreciated. This exacerbates many key challenges that older adults may face. It also undermines the many positive aspects of late life that are of tremendous value at both an individual and societal level. We propose a new approach to elevate health and well-being in late life by optimizing late-life Brain Capital. This form of capital prioritizes brain skills and brain health in a brain economy, which the challenges and opportunities of the 21st-century demands. This approach incorporates investing in late-life Brain Capital, developing initiatives focused on building late-life Brain Capital.

Keywords: Aging; Brain health; Innovation; Mental disorders; Neuroscience; Psychiatry.

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References

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Investing in Late-Life Brain Capital

Affiliations

Investing in Late-Life Brain Capital

Authors

Affiliations

Erratum in

Abstract

References

Grants and funding

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