Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2022 Jun;37(7):553-561.
doi: 10.1177/08830738221047668. Epub 2022 May 22.

Impact of the Updated Guideline for Pediatric Brain Death Determination on Current Practice

Affiliations

Impact of the Updated Guideline for Pediatric Brain Death Determination on Current Practice

Conrad Krawiec et al. J Child Neurol. 2022 Jun.

Abstract

Background: A guideline to determine pediatric brain death was updated in 2011. It is unknown how pediatric intensivists have accepted and adopted the revised guideline into clinical practice. Methods: We surveyed US pediatric critical care attending physicians July 2013 to September 2013 and February 2020 to May 2020. Brain death testing practices and utilization of the 2011 pediatric and neonatal brain death guideline were assessed. Results: The 2020 respondents found that the revised pediatric brain death guideline were useful in clinical practice (93.7% vs 83.3%, P = .0484) and provided more consistency and clarity (73.2% vs 63.1%, P = .0462) when compared to 2013 respondents. Conclusion: This study demonstrates that with defined criteria, survey participants reported increased clarity and consistency. Findings from our study indicate that in clinical practice there is no significant deviation from the minimum requirements to determine brain death in children as outlined in the 2011 guideline.

Keywords: brain; children; pediatrics; quality of life.

PubMed Disclaimer

Conflict of interest statement

Declaration of Conflicting Interests: The authors have no potential conflicts of interest with respect to the research, authorship, and/or publication of this article. Thomas A. Nakagawa receives author royalties from Wolters-Kluwer. UpToDate

Figures

Figure 1:
Figure 1:
Issues and Areas that Require Further Attention in Future Guideline Revisions

References

    1. Nakagawa TA, Ashwal S, Mathur M, Mysore M; Society of Critical Care Medicine, Section on Critical Care and Section on Neurology of American Academy of Pediatrics; Child Neurology Society. Clinical report—Guidelines for the determination of brain death in infants and children: an update of the 1987 task force recommendations. Pediatrics. 2011;128(3):e720–e740. - PubMed
    1. Wang HH, Varelas PN, Henderson GV, Wijdicks EFM, Greer DM. Improving uniformity in brain death determination policies over time. Neurology. 2017;88(6):562–568. 7 - PMC - PubMed
    1. Greer DM, Wang HH, Robinson JD, Varelas PN, Henderson GV, Wijdicks EFM. Variability of Brain Death Policies in the United States. JAMA Neurol. 2016;73(2):213–218. - PubMed
    1. Greer DM, Shemie SD, Lewis A, et al. Determination of Brain Death/Death by Neurologic Criteria: The World Brain Death Project. JAMA. 2020;324(11):1078–1097. - PubMed
    1. Harris PA, Taylor R, Thielke R, Payne J, Gonzalez N, Conde JG. Research Electronic Data Capture (REDCap) - A metadata-driven methodology and workflow process for providing translational research informatics support. J Biomed Inform. 2009;42(2):377–381. - PMC - PubMed

Publication types