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. 2022 May 23;37(3):356-369.
doi: 10.21470/1678-9741-2020-0731.

Cross-Cultural Translation into Brazilian Portuguese and Validation of the Oral Anticoagulation Knowledge Tool (AKT-Br)

Felipe F Mainka  1 , Vinicius L Ferreira  1 , Antonio M Mendes  2 , Gustavo L Marques  2 , Cassyano J Correr  3 , Fernanda S Tonin  1   4 , Roberto Pontarolo  3
Affiliations

Cross-Cultural Translation into Brazilian Portuguese and Validation of the Oral Anticoagulation Knowledge Tool (AKT-Br)

Felipe F Mainka et al. Braz J Cardiovasc Surg. .

Abstract

Introduction: Oral anticoagulants are the treatment of choice for diverse types of coagulation disorders. Warfarin is widely used by the Brazilian population, possibly due to its lower cost than other oral anticoagulants. However, it has a high risk of serious adverse effects if used incorrectly. The Anticoagulation Knowledge Tool (AKT) can assess a patient's knowledge about her/his oral anticoagulant therapy and can assist health professionals in identifying patients with difficulties in adherence. This study aimed to translate, culturally adapt, and validate the AKT into Brazilian Portuguese.

Methods: After a standard forward-backward procedure to translate the AKT into Brazilian Portuguese (AKT-Br), a version of the instrument was applied in three groups (patients, pharmacists, and the general population). The reliability of the AKT-Br was tested using an internal consistency measure and test-retest. The validity of the instrument was confirmed with data from the contrasted groups. All statistical analyses were performed with RStudio.

Results: The median scores obtained with the AKT-Br were 29.0, 17.0, and 7.5 for pharmacists, patients, and the general population, respectively (maximum score of 35 points). There was moderate internal consistency for the instrument and test-retest reliability was satisfactory. Analysis of variance for validity of the groups revealed a significant relationship between the total score and the evaluated groups.

Conclusion: The ATK-Br is a reliable and valid tool to assess knowledge about oral anticoagulants. AKT-Br can be used in clinical practice as an auxiliary tool to improve patient care through personalised educational interventions.

Keywords: Anticoagulants; Decision Support Techniques; Medication Adherence; Reproducibility of Results; Surveys and Questionnaires; Translating; Warfarin.

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Conflict of interest statement

No conflict of interest.

Figures

Fig. 1
Fig. 1
Total score comparison between groups/Tukey’s post hoc test showed significant differences (P<0.001) in comparing the means of all the groups (pharmacists vs. patients; pharmacists vs. population; patients vs. population).
See this image and copyright information in PMC

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