TKT deficiency puts T_regs to rest

Affiliations

Comment

Margarita Dominguez-Villar. Nat Metab. 2022 May.

. 2022 May;4(5):503-504.

doi: 10.1038/s42255-022-00574-0.

¹ Department of Infectious Diseases, Imperial College London, London, UK. m.dominguez-villar@imperial.ac.uk.

No abstract available

Comment on

Non-oxidative pentose phosphate pathway controls regulatory T cell function by integrating metabolism and epigenetics.
Liu Q, Zhu F, Liu X, Lu Y, Yao K, Tian N, Tong L, Figge DA, Wang X, Han Y, Li Y, Zhu Y, Hu L, Ji Y, Xu N, Li D, Gu X, Liang R, Gan G, Wu L, Zhang P, Xu T, Hu H, Hu Z, Xu H, Ye D, Yang H, Li B, Tong X. Liu Q, et al. Nat Metab. 2022 May;4(5):559-574. doi: 10.1038/s42255-022-00575-z. Epub 2022 May 23. Nat Metab. 2022. PMID: 35606596

1. Michalek, R. D. et al. J. Immunol. 186, 3299–3303 (2011). - DOI
1. Procaccini, C. et al. Immunity 44, 406–421 (2016). - DOI
1. Soto-Heredero, G., Gómez de Las Heras, M. M., Gabandé-Rodríguez, E., Oller, J. & Mittelbrunn, M. FEBS J. 287, 3350–3369 (2020). - DOI
1. Baardman, J. et al. Cell Rep. 25, 2044–2052.e5 (2018). - DOI
1. Britt, E. C. et al. Nat. Metab. 4, 389–403 (2022). - DOI