Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2022 Aug;145(1):27-35.
doi: 10.1007/s10633-022-09875-x. Epub 2022 May 24.

Visual function during and after an acute central serous chorioretinopathy episode

Peter Kiraly  1   2 , Jaka Smrekar  3 , Polona Jaki Mekjavić  4   5   6
Affiliations

Visual function during and after an acute central serous chorioretinopathy episode

Peter Kiraly et al. Doc Ophthalmol. 2022 Aug.

Abstract

Purpose: To evaluate visual function parameters during and after an acute central serous chorioretinopathy (CSC) episode.

Methods: A prospective study included 19 fovea involving acute CSC patients with episode resolution within 3 months from the episode onset. Optical coherence tomography, best corrected visual acuity (BCVA), contrast sensitivity (CS), microperimetry (MP), and multifocal electroretinography (mfERG) were performed at baseline, 3 and 6 months from the episode onset. In a sub analysis, patients were divided into groups with greater (gMV, N = 9) and lower (lMV, N = 10) macular volume at presentation, and functional outcomes were observed.

Results: BCVA (p < 0.001), average CS (CS-A) (p < 0.001), average retinal sensitivity (MP-A) (p < 0.001), mfERG amplitude densities in the first and second ring (mfERG-A1, p < 0.001; mfERG-A2, p = 0.017), and implicit times in the first, second, and third ring (mfERG-IT1, p = 0.024; mfERG-IT2, p = 0.002; mfERG-IT3, p = 0.018) improved with episode resolution 3 months after the episode onset. From 3 to 6 months after the episode onset, only CS-A (p = 0.045) continued to improve. Patients in the gMV group had lower mfERG-A1 (p = 0.017) and central retinal sensitivity (MP-C, p = 0.05) 6 months from the episode onset.

Conclusions: Although all functional parameters mostly improve with CSC episode resolution, only CS continues to improve thereafter. Patients with greater MV at presentation have worse functional outcomes. Visual function impairment in acute CSC patients is confined to the topographical area of subretinal fluid detachment.

Keywords: Central serous chorioretinopathy; Contrast sensitivity; Electrophysiology; Functional outcomes; Microperimetry; mfERG.

PubMed Disclaimer

References

    1. Daruich A, Matet A, Dirani A, Bousquet E, Zhao M, Farman N et al (2015) Central serous chorioretinopathy: recent findings and new physiopathology hypothesis. Prog Retin Eye Res 48:82–118 - DOI
    1. Daruich A, Matet A, Marchionno L, De Azevedo JD, Ambresin A, Mantel I et al (2017) Acute central serous chorioretinopathy: factors influencing episode duration. Retina 37(10):1905–1915 - DOI
    1. Lourthai P, Bhurayanontachai P (2017) Pattern of contrast sensitivity changes in acute central serous chorioretinopathy. J Ophthalmol 2017:9053932 - DOI
    1. Roisman L, Ribeiro JC, Fechine FV, Lavinsky D, Moraes N, Campos M et al (2014) Does microperimetry have a prognostic value in central serous chorioretinopathy? Retina (Philadelphia, Pa) 34(4):713–718 - DOI
    1. Huang S, Wu D, Jiang F, Wu L, Liang J, Luo G et al (2002) The multifocal electroretinogram in central serous chorioretinopathy. Ophthalmic Physiological Optics 22(3):244–247 - DOI

Publication types

LinkOut - more resources