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Case Reports
. 2022 Jun;28(6):1269-1273.
doi: 10.3201/eid2806.212246.

Identification of Human Case of Avian Influenza A(H5N1) Infection, India

Varsha Potdar, Megha Brijwal, Rakesh Lodha, Pragya Yadav, Santosh Jadhav, Manohar Lal Choudhary, Aashish Choudhary, Veena Vipat, Nivedita Gupta, Ashok Kumar Deorari, Lalit Dar, Priya Abraham
Case Reports

Identification of Human Case of Avian Influenza A(H5N1) Infection, India

Varsha Potdar et al. Emerg Infect Dis. 2022 Jun.

Abstract

A 11-year-old boy with acute myeloid leukemia was brought for treatment of severe acute respiratory infection in the National Capital Region, New Delhi, India. Avian influenza A(H5N1) infection was laboratory confirmed. Complete genome analysis indicated hemagglutinin gene clade 2.3.2.1a. We found the strain to be susceptible to amantadine and neuraminidase inhibitors.

Keywords: India; avian influenza; influenza; influenza A(H5N1); respiratory infections; viruses; zoonoses.

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Figures

Figure 1
Figure 1
Hemagglutinin gene phylogenetic tree of avian influenza viruses, constructed using the neighbor-joining method as implemented in MEGA 7 (https://www.megasoftware.net). Blue text indicates the study strains (clinical and isolate); shaded area represents the Bangladesh and India strains in clade 2.3.2.1a. Gs/Guangdong/1/96 was used as the outgroup sequence. Scale bar indicates number of nucleotide substitutions per site.
Figure 2
Figure 2
Neuraminidase gene phylogenetic tree constructed using the neighbor-joining method as implemented in MEGA 7 (https://www.megasoftware.net). Blue text indicates the study strains (clinical and isolate); shaded area represents the Bangladesh and India strains in clade 2.3.2.1a. Gs/Guangdong/1/96 was used as the outgroup sequence. Scale bar indicates number of nucleotide substitutions per site.
See this image and copyright information in PMC

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