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Randomized Controlled Trial
. 2023 Jun;135(11-12):291-300.
doi: 10.1007/s00508-022-02037-8. Epub 2022 May 25.

Comparison between exercise therapy and non-hydrolyzed collagen (UC-II) in functionality and quality of life in women with knee osteoarthritis : A randomized controlled clinical trial

Érika Thatyana Nascimento Santana  1 , Saulo da Cunha Machado  2 , Viviane Nascimento Brandão Lima  1 , Valter Joviniano DeSantana Filho  1 , Leonardo Yung Dos Santos Maciel  1 , Jader Pereira de Farias Neto  1 , Henrique Douglas Melo Coutinho  3 , Natália Martins  4 , Walderi Monteiro da Silva Júnior  1 , Lucindo J Quintans Júnior  1
Affiliations
Randomized Controlled Trial

Comparison between exercise therapy and non-hydrolyzed collagen (UC-II) in functionality and quality of life in women with knee osteoarthritis : A randomized controlled clinical trial

Érika Thatyana Nascimento Santana et al. Wien Klin Wochenschr. 2023 Jun.

Erratum in

Abstract

Background: Knee osteoarthritis (OA) is characterized by a progressive degeneration of cartilage and menisci, leading to pain and locomotor disability. Here, we aimed to assess the effect of an exercise protocol and the oral use of non-hydrolyzed collagen (UC-II) on the functionality and quality of life of women with knee OA.

Material and methods: Individuals were divided into three groups (CG [control group]; MG [medication group]; EG [exercise group]). In the CG there was no intervention, while MG received an oral dose (1 capsule/day) of UC-II and the EG held 12 sessions of an exercise protocol.

Results: In the functionality tests (6-min walk test, 6MWT and timed up and go test [TUG]) the EG (p < 0.001/p = 0.020) and MG (p = 0.010/p = 0.010) revealed a significant improvement when compared to the CG. In the analysis of quality of life by WOMAC, a significant improvement was found only in the EG (p = 0.030) when compared to the CG; the same happened in the stiffness domain (EG, p = 0.010), despite in the pain domain, both the EG (p < 0.001) and the MG (p = 0.060) were better than the CG.

Conclusion: Data obtained here reveal that an exercise protocol and UC-II have similar effects for functionality, despite exercise being superior in promoting the quality of life score.

Keywords: Cartilage; Chronic pain; Loss of flexibility; Pain; Risk factors; Tenderness.

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References

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