Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 1987 Jan;7(1):532-4.
doi: 10.1128/mcb.7.1.532-534.1987.

Cell cycle-dependent effects on deoxyribonucleotide and DNA labeling by nucleoside precursors in mammalian cells

J M Leeds, C K Mathews

Cell cycle-dependent effects on deoxyribonucleotide and DNA labeling by nucleoside precursors in mammalian cells

J M Leeds et al. Mol Cell Biol. 1987 Jan.

Abstract

dCTP pools equilibrated to equivalent specific activities in Chinese hamster ovary cells or in nuclei after incubation of cells with radiolabeled nucleosides, indicating that dCTP in nuclei does not constitute a distinct metabolic pool. In the G1 phase, [5-3H]deoxycytidine labeled dCTP to unexpectedly high specific activities. This may explain reports of replication-excluded DNA precursor pools.

PubMed Disclaimer

References

    1. Nat New Biol. 1973 May 23;243(125):105-7 - PubMed
    1. Mol Cell Biol. 1985 Dec;5(12):3443-50 - PubMed
    1. Biochem Biophys Res Commun. 1979 May 14;88(1):16-22 - PubMed
    1. J Clin Invest. 1980 Jan;65(1):26-36 - PubMed
    1. J Biol Chem. 1980 Jul 25;255(14):6640-5 - PubMed

Publication types

LinkOut - more resources