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. 1987 Apr;326(6112):466-70.
doi: 10.1038/326466a0.

Differentiated parental DNA strands confer developmental asymmetry on daughter cells in fission yeast

A J Klar

Differentiated parental DNA strands confer developmental asymmetry on daughter cells in fission yeast

A J Klar. Nature. 1987 Apr.

Abstract

The two strands of the DNA molecule are complementary but not identical. Hence, upon semiconservative replication, different parental DNA strands are segregated to daughter cells. A molecular analysis suggests that the process of fission yeast mating-type interconversion uses asymmetry of the DNA strands to generate a regular lineage of cellular differentiation.

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