Autistic symptomatology in UHR patients: A preliminary report

Michele Ribolsi¹, Giuliano Albergo², Federico Fiori Nastro³, Martina Pelle³, Valentina Contri², Cinzia Niolu³, Vincenzo Di Lazzaro², Alberto Siracusano³, Giorgio Di Lorenzo⁴

Affiliations

¹ Unit of Neurology, Neurophysiology, Neurobiology and Psychiatry, Department of Medicine, University Campus Bio-Medico of Rome, via Álvaro del Portillo, 21, 00128 Rome, Italy. Electronic address: michele.ribolsi@policlinicocampus.it.
² Unit of Neurology, Neurophysiology, Neurobiology and Psychiatry, Department of Medicine, University Campus Bio-Medico of Rome, via Álvaro del Portillo, 21, 00128 Rome, Italy.
³ Chair of Psychiatry, Department of Systems Medicine, University of Rome Tor Vergata, Psychiatry and Clinical Psychology Unit, Fondazione Policlinico Tor Vergata, Rome, Italy.
⁴ Chair of Psychiatry, Department of Systems Medicine, University of Rome Tor Vergata, Psychiatry and Clinical Psychology Unit, Fondazione Policlinico Tor Vergata, Rome, Italy; IRCCS - Fondazione Santa Lucia, Rome, Italy.

PMID: 35617823
DOI: 10.1016/j.psychres.2022.114634

Autistic symptomatology in UHR patients: A preliminary report

Michele Ribolsi et al. Psychiatry Res. 2022 Jul.

. 2022 Jul:313:114634.

doi: 10.1016/j.psychres.2022.114634. Epub 2022 May 14.

Authors

Michele Ribolsi¹, Giuliano Albergo², Federico Fiori Nastro³, Martina Pelle³, Valentina Contri², Cinzia Niolu³, Vincenzo Di Lazzaro², Alberto Siracusano³, Giorgio Di Lorenzo⁴

Affiliations

¹ Unit of Neurology, Neurophysiology, Neurobiology and Psychiatry, Department of Medicine, University Campus Bio-Medico of Rome, via Álvaro del Portillo, 21, 00128 Rome, Italy. Electronic address: michele.ribolsi@policlinicocampus.it.
² Unit of Neurology, Neurophysiology, Neurobiology and Psychiatry, Department of Medicine, University Campus Bio-Medico of Rome, via Álvaro del Portillo, 21, 00128 Rome, Italy.
³ Chair of Psychiatry, Department of Systems Medicine, University of Rome Tor Vergata, Psychiatry and Clinical Psychology Unit, Fondazione Policlinico Tor Vergata, Rome, Italy.
⁴ Chair of Psychiatry, Department of Systems Medicine, University of Rome Tor Vergata, Psychiatry and Clinical Psychology Unit, Fondazione Policlinico Tor Vergata, Rome, Italy; IRCCS - Fondazione Santa Lucia, Rome, Italy.

PMID: 35617823
DOI: 10.1016/j.psychres.2022.114634

Abstract

Several studies have evaluated the level of autistic symptomatology in schizophrenia patients (SCZ) and ultra-high risk for psychosis (UHR) patients, but the data are not conclusive. Using the PANSS Autism Severity Score (PAUSS) scale, we found that the degree of autistic symptomatology in UHR patients is significantly lower compared to SCZ patients but higher than in patients with a mood disorder. Moreover, we found a significant correlation between autistic symptomatology and the severity of formal thought disorders, confirming Bleuler's hypothesis about autism and association disorders as core features of psychosis.

Keywords: Autism; Schizophrenia; Ultra High Risk.

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Autistic symptomatology in UHR patients: A preliminary report

Affiliations

Autistic symptomatology in UHR patients: A preliminary report

Authors

Affiliations

Abstract

MeSH terms

LinkOut - more resources

Full Text Sources

Medical