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Comment
. 2022 May 26;8(1):34.
doi: 10.1038/s41572-022-00367-5.

The role of tranexamic acid in trauma - a life-saving drug with proven benefit

Ian Roberts  1 , Francois-Xavier Ageron  2
Affiliations
Comment

The role of tranexamic acid in trauma - a life-saving drug with proven benefit

Ian Roberts et al. Nat Rev Dis Primers. .
No abstract available

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  • Trauma-induced coagulopathy.
    Moore EE, Moore HB, Kornblith LZ, Neal MD, Hoffman M, Mutch NJ, Schöchl H, Hunt BJ, Sauaia A. Moore EE, et al. Nat Rev Dis Primers. 2021 Apr 29;7(1):30. doi: 10.1038/s41572-021-00264-3. Nat Rev Dis Primers. 2021. PMID: 33927200 Free PMC article. Review.

References

    1. CRASH-2 trial collaborators. Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial. Lancet 376, 23–32 (2010). - DOI
    1. CRASH-2 collaborators. The importance of early treatment with tranexamic acid in bleeding trauma patients: an exploratory analysis of the CRASH-2 randomised controlled trial. Lancet 377, 1096–1101 (2011). - DOI
    1. CRASH-3 trial collaborators. Effects of tranexamic acid on death, disability, vascular occlusive events and other morbidities in patients with acute traumatic brain injury (CRASH-3): a randomised, placebo-controlled trial. Lancet 394, 1713–1723 (2019). - DOI
    1. Moore, E. E. et al. Trauma-induced coagulopathy. Nat. Rev. Dis. Primers 7, 30 (2021). - DOI
    1. Roberts, I. et al. Tranexamic acid in bleeding trauma patients: an exploration of benefits and harms. Trials 18, 48 (2017). - DOI

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