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Editorial
. 2022 Apr 29;4(6):100472.
doi: 10.1016/j.xkme.2022.100472. eCollection 2022 Jun.

Balanced Solutions Versus Saline to Reduce AKI: A #NephJC Editorial on the BaSICS Trial

Mythri Shankar  1 , Carlo Trinidad  2 , Elliot Koranteng Tannor  3 , Swapnil Hiremath  4 , Joel M Topf  5
Affiliations
Editorial

Balanced Solutions Versus Saline to Reduce AKI: A #NephJC Editorial on the BaSICS Trial

Mythri Shankar et al. Kidney Med. .
No abstract available

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Figures

Figure 1
Figure 1
A comparative table of important studies published.
Figure 2
Figure 2
(A) Twitter discussion about choice of outcome, sample size, and power. (B) Twitter discussion of BaSICS trial results changing clinical management choice. BaSICS, Balanced Solutions in Intensive Care Study.
See this image and copyright information in PMC

References

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    1. Cecconi M., Hofer C., Teboul J.L., et al. Fluid challenges in intensive care: the FENICE study: a global inception cohort study. Intensive Care Med. 2015;41(9):1529–1537. - PMC - PubMed
    1. Yunos N.M., Bellomo R., Hegarty C., Story D., Ho L., Bailey M. Association between a chloride-liberal vs chloride-restrictive intravenous fluid administration strategy and kidney injury in critically ill adults. JAMA. 2012;308(15):1566–1572. - PubMed
    1. Yunos N.M. Chloride High Level Of Resuscitation Infusion Delivered Evaluation (CHLORIDE) https://clinicaltrials.gov/ct2/show/NCT00885404
    1. Young P., Bailey M., Beasley R., et al. Effect of a buffered crystalloid solution vs saline on acute kidney injury among patients in the intensive care unit: the SPLIT randomized clinical trial. JAMA. 2015;314(16):1701–1710. - PubMed

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