Neurosurgery in a patient with severe hemophilia B: an experience using eftrenonacog alfa as perioperative management
- PMID: 35620255
- PMCID: PMC9127245
- DOI: 10.1002/ccr3.5848
Neurosurgery in a patient with severe hemophilia B: an experience using eftrenonacog alfa as perioperative management
Abstract
Extended half-life FIX (EHL-FIX) concentrates have been developed with the purpose of reducing the frequency of infusions in patients with severe or moderate hemophilia B. We describe the case of a 63-year-old patient with severe hemophilia B (sHB) treated with FIX-Fc fusion protein (rFIXFc) who underwent neurosurgery.
Keywords: anesthesia; haemophilia B; hematology; neuosurgery; pharmacology; rFIX‐Fc.
© 2022 The Authors. Clinical Case Reports published by John Wiley & Sons Ltd.
Conflict of interest statement
None.
References
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- Powell JS, Apte S, Chambost H, et al. Long‐acting recombinant factor IX Fc fusion protein (rFIXFc) for perioperative management of subjects with haemophilia B in the phase 3 B‐LONG study. Br J Haematol. 2015;168(1):124‐134. - PubMed
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