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Review
. 2022 Apr 16;34(1):1-15.
doi: 10.4103/joco.joco_135_21. eCollection 2022 Jan-Mar.

Global Prevalence and Causes of Visual Impairment and Blindness in Children: A Systematic Review and Meta-Analysis

Abbasali Yekta  1 , Elham Hooshmand  2 , Mohammad Saatchi  3 , Hadi Ostadimoghaddam  4 , Amir Asharlous  5 , Azadeh Taheri  6 , Mehdi Khabazkhoob  7
Affiliations
Review

Global Prevalence and Causes of Visual Impairment and Blindness in Children: A Systematic Review and Meta-Analysis

Abbasali Yekta et al. J Curr Ophthalmol. .

Abstract

Purpose: To determine the global prevalence and common causes of visual impairment (VI) and blindness in children.

Methods: In this meta-analysis, a structured search strategy was applied to search electronic databases including PubMed, Scopus, and Web of Science, as well as the list of references in the selected articles to identify all population-based cross-sectional studies that concerned the prevalence of VI and blindness in populations under 20 years of age up to January 2018, regardless of the publication date and language, gender, region of residence, or race. VI was reported based on presenting visual acuity (PVA), uncorrected visual acuity (UCVA), and best corrected visual acuity (BCVA) of equal to 20/60 or worse in the better eye. Blindness was reported as visual acuity worse than 20/400 in the better eye.

Results: In the present study, 5711 articles were identified, and the final analyses were done on 80 articles including 769,720 people from twenty-eight different countries. The prevalence of VI based on UCVA was 7.26% (95% confidence interval [CI]: 4.34%-10.19%), PVA was 3.82% (95% CI: 2.06%-5.57%), BCVA was 1.67% (95% CI 0.97%-2.37%), and blindness was 0.17% (95% CI: 0.13%-0.21%). Refractive errors were the most common cause of VI in the subjects of selected articles (77.20% [95% CI: 73.40%-81.00%]). The prevalence of amblyopia was 7.60% (95% CI: 05.60%-09.10%) and congenital cataract was 0.60% (95% CI: 0.3%-0.9%).

Conclusion: Despite differences in the definition of VI and blindness, based on PVA, 3.82%, and based on BCVA, 1.67% of the examined samples suffer from VI.

Keywords: Blindness; Children; Low vision; Visual impairment.

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Conflict of interest statement

There are no conflicts of interest.

Figures

Figure 1
Figure 1
Flow of information through the different phases of the systematic review
Figure 2
Figure 2
Overall prevalence and subgroups of uncorrected visual acuity based on uncorrected visual acuity
Figure 3
Figure 3
Overall prevalence and subgroups of presenting visual acuity (PVA) based on PVA
Figure 4
Figure 4
Overall prevalence and subgroups of best corrected visual acuity (BCVA) based on BCVA
Figure 5
Figure 5
Overall prevalence and subgroups of blindness
See this image and copyright information in PMC

References

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