Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2022;14(1):18-22.
doi: 10.34172/jcvtr.2022.05. Epub 2022 Mar 12.

Effect of hyperglycemia treatment on complications rate after pediatric cardiac surgery

Bahman Naghipour  1 , Mahdieh Bagerpour  2 , Kamran Shadvar  1 , Samad E J Golzari  1 , Gholamreza Faridaalaee  3   4
Affiliations

Effect of hyperglycemia treatment on complications rate after pediatric cardiac surgery

Bahman Naghipour et al. J Cardiovasc Thorac Res. 2022.

Abstract

Introduction: The goal of this study was to elucidate harmful complications of intraoperative hyperglycemia following children cardiac surgery and benefits of insulin administration for accurate blood sugar controlling. Methods: this study is a Randomized clinical trial. We conducted this study in the operating room of shahid madani hospital. Fifty patients who were children under 12 years old undergone cardiac surgery using cardiopulmonary bypass (CPB). Intraoperative insulin infusion was administered intravenously targeting blood sugar levels of 110-140 mg/dL. Blood sugar and arterial blood gas (ABG) were measured every 30 min during operation. Results: Inotropes were used less in the study than the placebo group during surgery. The means of hospitalization and extubation time were more in the placebo group than the study group(P =0.03) and (P =0.005), respectively. However, the mean time of hospitalization in the ICU ward did not differ significantly between the two groups. Conclusion: Hyperglycemia has a relation with long time of intubation and hospitalization in ICU. These findings suggest the positive effect of accurate blood sugar control on reducing complication and hospitalization time in children undergoing cardiac surgery.

Keywords: Cardiac Surgical Procedures; Heart; Hyperglycemia; Pediatrics; Thoracic Surgery; Treatment and Complications.

PubMed Disclaimer

Figures

Figure 1
Figure 1
See this image and copyright information in PMC

References

    1. Agus MS, Steil GM, Wypij D, Costello JM, Laussen PC, Langer M. et al. Tight glycemic control versus standard care after pediatric cardiac surgery. N Engl J Med. 2012;367(13):1208–1219. doi: 10.1056/NEJMoa1206044. - DOI - PMC - PubMed
    1. Azarfarin R, Seyedhejazi M, Golzari SE, Bilehjani E, Ghabili K, Alizadehasl A. Do pediatric patients undergoing cardiac surgeries require larger-size cuffed endotracheal tubes? A prospective study. Paediatr Anaesth. 2013;23(3):228–232. doi: 10.1111/pan.12112. - DOI - PubMed
    1. Alaei F, Nakhostin-Davari P, Alaei M, Azarfarin R, Soleymani E. Postoperative outcome for hyperglycemic pediatric cardiac surgery patients. Pediatr Cardiol. 2012;33(1):21–26. doi: 10.1007/s00246-011-0060-3. - DOI - PubMed
    1. Moga MA, Manlhiot C, Marwali EM, McCrindle BW, Van Arsdell GS, Schwartz SM. Hyperglycemia after pediatric cardiac surgery: impact of age and residual lesions. Crit Care Med. 2011;39(2):266–272. doi: 10.1097/CCM.0b013e3181fee88e. - DOI - PubMed
    1. Verhoeven JJ, Hokken-Koelega AC, den Brinker M, Hop WC, van Thiel RJ, Bogers AJ. et al. Disturbance of glucose homeostasis after pediatric cardiac surgery. Pediatr Cardiol. 2011;32(2):131–138. doi: 10.1007/s00246-010-9829-z. - DOI - PMC - PubMed

LinkOut - more resources