Tracing back to one of the origins of immune evasion in pancreatic cancer
- PMID: 35623340
- DOI: 10.1016/j.ccell.2022.05.002
Tracing back to one of the origins of immune evasion in pancreatic cancer
Abstract
In this issue of Cancer Cell, Huang et al. identify the origin and function of a subset of pancreatic cancer-associated fibroblasts. This work further highlights the power of lineage-tracing models for dissecting the tumor microenvironment in pancreatic cancer and provides new knowledge toward the development of novel therapeutic strategies.
Copyright © 2022 Elsevier Inc. All rights reserved.
Conflict of interest statement
Declaration of interests The authors declare no competing interests.
Comment on
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Mesothelial cell-derived antigen-presenting cancer-associated fibroblasts induce expansion of regulatory T cells in pancreatic cancer.Cancer Cell. 2022 Jun 13;40(6):656-673.e7. doi: 10.1016/j.ccell.2022.04.011. Epub 2022 May 5. Cancer Cell. 2022. PMID: 35523176 Free PMC article.
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