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. 2022 Aug;45(4):2951-2959.
doi: 10.1007/s10143-022-01816-1. Epub 2022 May 27.

Sphenoid wing meningiomas: peritumoral brain edema as a prognostic factor in surgical outcome

Abdalrahman Nassar  1 , Volodymyr Smolanka  2 , Andriy Smolanka  2 , Dipak Chaulagain  2 , Oleg Devinyak  3
Affiliations

Sphenoid wing meningiomas: peritumoral brain edema as a prognostic factor in surgical outcome

Abdalrahman Nassar et al. Neurosurg Rev. 2022 Aug.

Abstract

Sphenoidal meningiomas constitute 18% of intracranial masses, and still present a difficult surgical challenge. PTBE has been associated with several complications and future recurrence. This study aims to evaluate the outcome of the operatively treated sphenoid wing meningiomas in relation to PTBE as a prognostic factor in a series of 65 patients. The clinical materials of 65 patients with SWM treated microsurgically between 2007 and 2020 were analyzed retrospectively. Follow-up ranged from 6 to 156 months (median, 86). Clinical outcomes include postoperative major neurological deficit, quality of life using KPS, recurrence, and mortality rates. The mean age of patients was 53.9 years (range 20-74), males 24.6% and females75.4%. An edema index (EI) of 1 (40%) was considered as absent edema, and EI > 1 (60%) indicated present edema. Total resection (Simpson I-II) was achieved in 64.6% and subtotal (Simpson IV) in 13.8%. Postoperative complications included vision impairment in 3 patients, motor weakness 6, third nerve palsy 6, intraoperative bleeding and edema 5, and MCA infarct 2, recurrence in 17% and 7.7% died. In univariate analysis, we found that the PTBE is one of the serious risk factors in the immediate surgical outcomes and complication, though more data is needed to support this claim, while having a negative effect on postoperative KPS at short-term follow up (χ2 = 6.44, p = 0.011). PTBE was associated with decline in KPS and quality of life in the early postoperative period (three months) while showing no significant effect at long-term outcomes.

Keywords: Mortality; Peritumoral brain edema; Quality of life; Sphenoid wing meningioma.

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