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Randomized Controlled Trial
. 2022 May 11;19(10):5847.
doi: 10.3390/ijerph19105847.

The Role of Tobacco Smoking in the Efficacy of Brief Alcohol Intervention: Results from a Randomized Controlled Trial

Affiliations
Randomized Controlled Trial

The Role of Tobacco Smoking in the Efficacy of Brief Alcohol Intervention: Results from a Randomized Controlled Trial

Filipa Krolo et al. Int J Environ Res Public Health. .

Abstract

This study investigated whether tobacco smoking affected outcomes of brief alcohol interventions (BAIs) in at-risk alcohol-drinking general hospital patients. Between 2011 and 2012 among patients aged 18−64 years, 961 patients were allocated to in-person counseling (PE), computer-based BAI containing computer-generated individual feedback letters (CO), and assessment only. PE and CO included contacts at baseline, 1, and 3 months. After 6, 12, 18, and 24 months, self-reported reduction of alcohol use per day was assessed as an outcome. By using latent growth curve models, self-reported smoking status, and number of cigarettes per day were tested as moderators. In PE and CO, alcohol use was reduced independently of smoking status (IRRs ≤ 0.61, ps < 0.005). At month 24, neither smoking status nor number of cigarettes per day moderated the efficacy of PE (IRR = 0.69, ps > 0.05) and CO (IRR = 0.85, ps > 0.05). Up to month 12, among persons smoking ≤ 19 cigarettes per day, the efficacy of CO increased with an increasing number of cigarettes (ps < 0.05). After 24 months, the efficacy of PE and CO that have been shown to reduce drinking did not differ by smoking status or number of cigarettes per day. Findings indicate that efficacy may differ by the number of cigarettes in the short term.

Keywords: alcohol; brief intervention; computer invention; counseling; efficacy; moderator; tobacco.

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Conflict of interest statement

The authors declare no conflict of interest. The funders had no role in the design of the study; in the collection, analyses, or interpretation of data; in the writing of the manuscript, or in the decision to publish the results.

Figures

Figure 2
Figure 2
Effect of the computer-based BAI compared to assessment only.
Figure 3
Figure 3
Plot of regions of significance for the effects of the computer-based BAI compared to assessment only.
Figure 1
Figure 1
Participant flow by the study group.

References

    1. World Health Organization . Global Status Report on Alcohol and Health—2018. WHO Press; Geneva, Switzerland: 2018.
    1. World Health Organization . WHO Global Report: Mortality Attributable to Tobacco. World Health Organization; Geneva, Switzerland: 2012.
    1. Wild C.P., Weiderpass E., Stuart B.W. World Cancer Report: Cancer Research for Cancer Prevention. International Agency for Research on Cancer; Lyon, France: 2020.
    1. Kalman D., Kim S., DiGirolamo G., Smelson D., Ziedonis D.M. Addressing tobacco use disorder in smokers in early remission from alcohol dependence: The case for integrating smoking cessation services in substance use disorder treatment programs. Clin. Psychol. Rev. 2010;30:12–24. doi: 10.1016/j.cpr.2009.08.009. - DOI - PMC - PubMed
    1. Maso L.D., Torelli N., Biancotto E., Di Maso M., Gini A., Franchin G., Levi F., La Vecchia C., Serraino D., Polesel J. Combined effect of tobacco smoking and alcohol drinking in the risk of head and neck cancers: A re-analysis of case–control studies using bi-dimensional spline models. Eur. J. Epidemiol. 2016;31:385–393. doi: 10.1007/s10654-015-0028-3. - DOI - PubMed

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