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. 2022 May 19;11(10):2879.
doi: 10.3390/jcm11102879.

Woven EndoBridge in Wide-Neck Bifurcation Aneurysms: Digital Subtraction Angiography at 3-Year Follow-Up

Affiliations

Woven EndoBridge in Wide-Neck Bifurcation Aneurysms: Digital Subtraction Angiography at 3-Year Follow-Up

Carmelo Stanca et al. J Clin Med. .

Abstract

Introduction: The Woven EndoBridge (WEB) device is a self-expanding intrasaccular braided-wire device for the treatment of wide-neck bifurcation aneurysms (WNBAs). Even though this device has an excellent safety profile and a low risk of rebleeding, little is known about its long-term effects.

Material and methods: All patients treated with WEB due to ruptured WNBAs were subjected to follow-up digital subtraction angiography (DSA) at 2 and 3 years after device deployment. The degree of residual neck was assessed through BOSS, Lubicz, and WEBCAST scales. Data on modified Rankin scale (mRS), bleeding events, and ischemic events occurring during this time period were collected as well. Lastly, overall and procedure-related mortality rates were calculated.

Results: A total of 21 patients were treated between 1 January 2016, and 31 December 2018. DSA demonstrated a patency grade of 57.1% and 61.1% at 2 and 3 years, respectively. The overall 2-year mortality rate due to causes unrelated to the aneurysm was 14.3%. None of the patients were retreated between the 2- and the 3-year follow-up. No rebleeding or stroke events occurred during the follow-up.

Conclusions: WEB-treated ruptured aneurysms showed an excellent degree of stability over time. The overall mortality rate-unrelated to the procedure-observed in our sample was higher than what reported in the literature, a possible bias associated with the COVID-19 pandemic.

Keywords: Woven EndoBridge; aneurysm; device; endovascular treatment; hemorrhage; interventional radiology; subarachnoid.

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Conflict of interest statement

The authors declare no conflict of interest.

Figures

Figure 1
Figure 1
The images show a wide neck aneurysm of the apex of the basilar artery treated using WEB 3 × 2 mm. (a) not-substracted DSA at 3-years, (b) substracted DSA at 3-years. An aneurysm adeguate occlusion was detected and confirmed by 3D protocol.

References

    1. Nichols D.A., Brown R.D., Meyer F.B. Coils or clips in subarachnoid haemorrhage? Lancet. 2002;360:1262–1263. doi: 10.1016/S0140-6736(02)11353-5. - DOI - PubMed
    1. Ding Y., Lewis D., Kadirvel R., Dai D., Kallmes D. The Woven EndoBridge: A New Aneurysm Occlusion Device. Am. J. Neuroradiol. 2011;32:607–611. doi: 10.3174/ajnr.A2399. - DOI - PMC - PubMed
    1. Pierot L., Moret J., Barreau X., Szikora I., Herbreteau D., Turjman F., Holtmannspötter M., Januel A.-C., Costalat V., Fiehler J., et al. Safety and efficacy of aneurysm treatment with WEB in the cumulative population of three prospective, multicenter series. J. Neurointerv. Surg. 2018;10:553–559. doi: 10.1136/neurintsurg-2017-013448. - DOI - PMC - PubMed
    1. Arthur A.S., Molyneux A., Coon A.L., Saatci I., Szikora I., Baltacioglu F., Sultan A., Hoit D., Almandoz J.E.D., Elijovich L., et al. The safety and effectiveness of the Woven EndoBridge (WEB) system for the treatment of wide-necked bifurcation aneurysms: Final 12-month results of the pivotal WEB Intrasaccular Therapy (WEB-IT) Study. J. Neurointerv. Surg. 2019;11:924–930. doi: 10.1136/neurintsurg-2019-014815. - DOI - PMC - PubMed
    1. Pierot L., Moret J., Turjman F., Herbreteau D., Raoult H., Barreau X., Velasco S., Desal H., Januel A.-C., Courtheoux P., et al. WEB Treatment of Intracranial Aneurysms: Clinical and Anatomic Results in the French Observatory. Am. J. Neuroradiol. 2016;37:655–659. doi: 10.3174/ajnr.A4578. - DOI - PMC - PubMed

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