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Review
. 2022 May 9;10(5):737.
doi: 10.3390/vaccines10050737.

A Review of Different Vaccines and Strategies to Combat COVID-19

Srinivasan Sabitha  1 , Nagarajan Shobana  1 , Pandurangan Prakash  1 , Sathiyamoorthy Padmanaban  2   3 , Mahendran Sathiyashree  1 , Subramanian Saigeetha  4 , Srikumar Chakravarthi  5 , Saji Uthaman  6 , In-Kyu Park  2   3 , Antony V Samrot  5   7
Affiliations
Review

A Review of Different Vaccines and Strategies to Combat COVID-19

Srinivasan Sabitha et al. Vaccines (Basel). .

Abstract

In December 2019, an unknown viral infection emerged and quickly spread worldwide, resulting in a global pandemic. This novel virus caused severe pneumonia and acute respiratory distress syndrome caused by Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2). It has caused 6.25 millions of deaths worldwide and remains a major concern for health, society, and the economy. As vaccination is one of the most efficient ways to combat this pandemic, different vaccines were developed in a short period. This review article discusses how coronavirus affected the top nations of the world and the vaccines being used for the prevention. Amongst the vaccines, some vaccines have already been approved, and some have been involved in clinical studies. The article also provides insight into different COVID-19 vaccine platforms, their preparation, working, efficacy, and side effects.

Keywords: SARS-CoV-2 infection; cell-mediated immunity; humoral immunity; polymeric nanovaccine.

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Conflict of interest statement

The authors declare no conflict of interest.

Figures

Figure 1
Figure 1
Schematic overview of COVID-19 transmission and lifecycle: (a) Prevention, transmission, signs and symptoms, and (b) lifecycle of coronavirus (Inspired from Liu et al. [18]).
Figure 1
Figure 1
Schematic overview of COVID-19 transmission and lifecycle: (a) Prevention, transmission, signs and symptoms, and (b) lifecycle of coronavirus (Inspired from Liu et al. [18]).
Figure 2
Figure 2
Graphical representation of COVID-19 infections, deaths, and recovered cases in 10 different countries (as of 28 February 2022).
Figure 3
Figure 3
Vaccine strategies and immune response.
Figure 4
Figure 4
Prevention of diseases using antioxidants.
See this image and copyright information in PMC

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