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. 2022 Jun;37(6).
doi: 10.1002/gps.5761.

Predictors of the change in burden, strain, mood, and quality of life among caregivers of Parkinson's disease patients

Diego Santos-García  1 , Teresa de Deus Fonticoba  2 , Carlos Cores Bartolomé  1 , Maria Cristina Íñiguez Alvarado  1 , Maria J Feal Panceiras  1 , Ester Suárez Castro  2 , Héctor Canfield  2 , Cristina Martínez Miró  1 , Silvia Jesús  3   4 , Miquel Aguilar  5 , Pau Pastor  5 , Lluís Planellas  6 , Marina Cosgaya  7 , Juan García Caldentey  8 , Nuria Caballol  9 , Ines Legarda  10 , Jorge Hernández Vara  4   11 , Iria Cabo  12 , Lydia López Manzanares  13 , Isabel González Aramburu  4   14 , Maria A Ávila Rivera  15 , Víctor Gómez Mayordomo  16 , Víctor Nogueira  17 , Víctor Puente  18 , Julio Dotor García-Soto  19 , Carmen Borrué  20 , Berta Solano Vila  21 , María Álvarez Sauco  22 , Lydia Vela  23 , Sonia Escalante  24 , Esther Cubo  25 , Francisco Carrillo Padilla  26 , Juan C Martínez Castrillo  27 , Pilar Sánchez Alonso  28 , Maria G Alonso Losada  29 , Nuria López Ariztegui  30 , Itziar Gastón  31 , Jaime Kulisevsky  4   32 , Marta Blázquez Estrada  33 , Manuel Seijo  12 , Javier Rúiz Martínez  34 , Caridad Valero  35 , Mónica Kurtis  36 , Oriol de Fábregues  11 , Jessica González Ardura  37 , Ruben Alonso Redondo  38 , Carlos Ordás  39 , Luis M López DíazL  40 , Darrian McAfee  41 , Pablo Martinez-Martin  4 , Pablo Mir  3   4 ; COPPADIS Study Group
Affiliations

Predictors of the change in burden, strain, mood, and quality of life among caregivers of Parkinson's disease patients

Diego Santos-García et al. Int J Geriatr Psychiatry. 2022 Jun.

Abstract

Background and objective: Caregiver burden in Parkinson's disease (PD) has been studied in many cross-sectional studies but poorly in longitudinal ones. The aim of the present study was to analyze the change in burden, strain, mood, and quality of life (QoL) after a 2-year follow-up in a cohort of caregivers of patients with PD and also to identify predictors of these changes.

Patients and methods: PD patients and their caregivers who were recruited from January/2016 to November/2017 from 35 centers of Spain from the COPPADIS cohort were included in the study. They were evaluated again at 2-year follow-up. Caregivers completed the Zarit Caregiver Burden Inventory (ZCBI), Caregiver Strain Index (CSI), Beck Depression Inventory-II (BDI-II), and EUROHIS-QOL 8-item index (EUROHIS-QOL8) at baseline (V0) and at 2-year follow-up (V2). General linear model repeated measure and lineal regression models were applied.

Results: Significant changes, indicating an impairment, were detected on the total score of the ZCBI (p < 0.0001), CSI (p < 0.0001), BDI-II (p = 0.024), and EUROHIS-QOL8 (p = 0.002) in 192 PD caregivers (58.82 ± 11.71 years old; 69.3% were females). Mood impairment (BDI-II; β = 0.652; p < 0.0001) in patients from V0 to V2 was the strongest factor associated with caregiver's mood impairment after the 2-year follow-up. Caregiver's mood impairment was the strongest factor associated with an increase from V0 to V2 on the total score of the ZCBI (β = 0.416; p < 0.0001), CSI (β = 0.277; p = 0.001), and EUROHIS-QOL (β = 0.397; p = 0.002).

Conclusion: Burden, strain, mood, and QoL were impaired in caregivers of PD patients after a 2-year follow-up. Mood changes in both the patient and the caregiver are key aspects related to caregiver burden increase.

Keywords: Parkinson's disease; burden; caregiver; mood; strain.

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References

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