Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
. 2022 Apr 6;21(3):76.
doi: 10.31083/j.jin2103076.

What we have learned to date from the omics approach to non-Alzheimer's dementias

Mehmet Demirci  1 , Ozge Altintas Kadirhan  2
Affiliations
Free article
Review

What we have learned to date from the omics approach to non-Alzheimer's dementias

Mehmet Demirci et al. J Integr Neurosci. .
Free article

Abstract

Worldwide, more than 50 million people live with dementia, and due to the rapidly aging population, dementia cases are expected to increase at least five times in 2050. 30%-40% of dementia cases are diagnosed as non-Alzheimer's dementia. Common subtypes of non-Alzheimer's dementia are known as vascular, Lewy body, and frontotemporal dementia. Despite advances in modern medicine, the mechanism of dementia is still not fully understood. The term "omics" is a general term and is used to comprehensively characterize molecules by functional and biological similarities, focusing on the basic biological processes of a living organism and these techniques have enabled us to examine the unknown areas of biology, such as the genome, transcriptome, proteome, microbiome, and metabolome. This review highlights the progress that has been made in omics research while noting the gaps in our knowledge.

Keywords: Cognitive impairment; Host; Microorganism; Non-Alzheimer's dementia; Omics.

PubMed Disclaimer

Conflict of interest statement

The authors declare no conflict of interest. MD and OAK are serving as one of the Guest Editors of this journal. We declare that MD and OAK had no involvement in the peer review of this article and has no access to information regarding its peer review. Full responsibility for the editorial process for this article was delegated to RF.

LinkOut - more resources