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Review
. 2022 Jun;36(2):397-421.
doi: 10.1016/j.idc.2022.01.006. Epub 2022 Feb 1.

COVID-19 in the Immunocompromised Host, Including People with Human Immunodeficiency Virus

Niyati Jakharia  1 , Aruna K Subramanian  2 , Adrienne E Shapiro  3
Affiliations
Review

COVID-19 in the Immunocompromised Host, Including People with Human Immunodeficiency Virus

Niyati Jakharia et al. Infect Dis Clin North Am. 2022 Jun.

Abstract

This review describes the incidence, epidemiology, and risk factors for mortality of COVID-19 in immunocompromised patients, including persons with human immunodeficiency virus. It describes various preventive measures, including vaccines and their effectiveness and the role of monoclonal antibodies for pre-exposure prophylaxis. It also reviews the different treatment options for immunocompromised individuals, including antivirals, monoclonal antibodies, and immunomodulators. Lastly, it describes the impact of COVID-19 on transplantation and continuity care of this population.

Keywords: CD4; COVID-19; HIV; Hematopoietic stem cell transplant; Immunocompromise; Immunosuppression; SARS-CoV-2; Solid organ transplant.

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References

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