Gene-drug potency screening in M. tuberculosis

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Luiz Pedro Sório de Carvalho. Nat Microbiol. 2022 Jun.

. 2022 Jun;7(6):743-744.

doi: 10.1038/s41564-022-01139-3.

¹ Mycobacterial Metabolism and Antibiotic Research Laboratory, The Francis Crick Institute, London, UK. luiz.carvalho@crick.ac.uk.

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CRISPRi chemical genetics and comparative genomics identify genes mediating drug potency in Mycobacterium tuberculosis.
Li S, Poulton NC, Chang JS, Azadian ZA, DeJesus MA, Ruecker N, Zimmerman MD, Eckartt KA, Bosch B, Engelhart CA, Sullivan DF, Gengenbacher M, Dartois VA, Schnappinger D, Rock JM. Li S, et al. Nat Microbiol. 2022 Jun;7(6):766-779. doi: 10.1038/s41564-022-01130-y. Epub 2022 May 30. Nat Microbiol. 2022. PMID: 35637331 Free PMC article.

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