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Case Reports
. 2022 Apr 12:77:103605.
doi: 10.1016/j.amsu.2022.103605. eCollection 2022 May.

Primary peritoneal high-grade serous carcinoma in a man: A case report

Abdelali Guellil  1   2 , Rachid Jabi  1   2 , Mohamed Yassine Mabrouk  1   2 , Laila Bouzayan  1   2 , Abdelali Merhoum  1   2 , Gérald Del Gallo  3 , Claire Godart  3 , Mohammed Bouziane  1   2
Affiliations
Case Reports

Primary peritoneal high-grade serous carcinoma in a man: A case report

Abdelali Guellil et al. Ann Med Surg (Lond). .

Abstract

Introduction and importance: Primary peritoneal serous carcinomas (PPSC) are exceedingly rare in male patients. Only a few cases were reported in the medical literature, it's diagnosis is difficult before surgery.

Case presentation: In this article, we describe the case of a patient who presented a high-grade primary peritoneal carcinoma, the diagnosis was suspected radiologically following an abdominopelvic computed tomography (CT).the patient underwent exploratory laparoscopic surgery with biopsy of several peritoneal nodules. Pathologic analysis of specimen confirmed the diagnosis of Primary peritoneal serous carcinomas. The patient died one month after his diagnosis while undergoing chemotherapy and palliative care.

Clinical discussion: PPSC is an inoperable malignancy, histology staining confirms the diagnosis, the chemotherapy and palliative care are the only offered treatment. The evolution of the disease is very dark with a poor prognosis.

Conclusion: We highlight the important of testicular examination to predict apparition of PPSC in the future.

Keywords: Diagnosis; High-grade primary peritoneal serous carcinoma; Histology; Male.

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Conflict of interest statement

The authors declared no potential conflicts of interests with respect to research, authorship and/or publication of the article.

Figures

Fig. 1
Fig. 1
A: Axial section of primary serous carcinoma of the peritoneum in a 77-year-old man showing the presence of a large dense nodular lesion with lobulated contours measuring 6 cm.
Fig. 2
Fig. 2
Visualization of multiple focal intrahepatic lesions of secondary appearance. The two target lesions are located in segment VIII (coronal section B), measuring 66 mm and 50 mm in maximum diameter. Another lesion is found in segment VII(axial section A), 4th lesion in segment III.
Fig. 3
Fig. 3
Positron emission tomography-computed tomography (PET/CT) finding. The nodular mass lesion shows intense FDG uptake in segment VII (B, D). Moderate to intense FDG uptake on large peripheral peritoneal structures (A, C).
Fig. 4
Fig. 4
Exeresis part of our exploratory laparoscopy.
Fig. 5
Fig. 5
Typical histological features of high-grade serous carcinoma. A. Nests of tumor cells separated from the surrounding stroma by a retraction space and associated with numerous psammoma bodies (hematoxylin-eosin, original magnification × 200). B. The tumor cells show high-grade nuclear atypia without conspicuous mitotic activity (hematoxylin-eosin, original magnification × 200).
See this image and copyright information in PMC

References

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