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Case Reports
. 2022 Apr 15:77:103632.
doi: 10.1016/j.amsu.2022.103632. eCollection 2022 May.

White-centered retinal hemorrhage revealing acute leukemia: A case report

Nadia Ben Abdesslem  1   2 , Nesrine Zaafrane  1   2 , Atf Ben Abderazek  1   2 , Ahmed Jabri  1   2 , Anis Mahjoub  1   2 , Chiraz Ben Youssef  1   2 , Hachemi Mahjoub  1   2 , Fethi Krifa  1   2 , Ahmed Mahjoub  1   2
Affiliations
Case Reports

White-centered retinal hemorrhage revealing acute leukemia: A case report

Nadia Ben Abdesslem et al. Ann Med Surg (Lond). .

Abstract

Retinal manifestations have been described as an inaugural manifestation of acute leukemia. Retinal hemorrhage, and in particular white-centered hemorrhages are among the most frequently observed signs. We report here the case of a 34-year-old Caucasian man with no medical history who presented to our emergency department with a decrease in visual acuity associated with asthenia. Ophthalmological examination revealed bilateral white-centered hemorrhages. The etiological assessment confirmed the diagnosis of acute myeloid leukemia. Whenever Roth spots are found in fundus examination, a complete ophthalmological examination along with a wide etiological investigation must be conducted.

Keywords: Acute myeloid leukemia; Case report; Roth spots; White-centered hemorrhage.

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Conflict of interest statement

The following authors have no financial disclosures: (Nadia Ben Abdessalem, Nesrine Zaafrane, Atf Ben Abderrazek, Ahmed Jabri, Anis Mahjoub, Chiraz Ben Youssef, Hachemi Mahjoub, Fathi Krifa, Ahmed Mahjoub).

Figures

Fig. 1
Fig. 1
Color fundus photograph (a) of right eye: A, and left eye: B, showing intraretinal and subhyaloid hemorrhages with Roth Spots. (For interpretation of the references to colour in this figure legend, the reader is referred to the Web version of this article.)
Fig. 2
Fig. 2
Swept source OCT of both eyes A: right eye, B: left eye, showing intraretinal and subhyaloid hemorrhages.
See this image and copyright information in PMC

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