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. 2022 Jun 1;107(6):1239-1242.
doi: 10.3324/haematol.2022.280920.

Introduction to a review series on the treatment of thrombocytopenic disorders: something old, something new

Affiliations

Introduction to a review series on the treatment of thrombocytopenic disorders: something old, something new

Francesco Rodeghiero. Haematologica. .
No abstract available

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Figures

Figure 1.
Figure 1.
Pathogenic mechanisms of congenital and acquired thrombocytopenia. The pathogenic mechanisms responsible for thrombocytopenia can be grouped into three categories: reduced production of platelets, increased consumption/destruction in the bloodstream, and increased destruction/entrapment in the spleen. The causes of thrombocytopenia are shown in the figure and many of them act through more than one pathogenic mechanism. Increased awareness of the many distinct forms of thrombocytopenia is a prerequisite for appropriate prevention, as in drug-associated thrombocytopenia, or for making a precise prognosis or planning comprehensive treatment exploiting as best possible the limited options available for the various different types of congenital and acquired thrombocytopenia.

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