Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Editorial
. 2022 May 18:12:17.
doi: 10.5334/tohm.697. eCollection 2022.

Clinical and Radiological Follow-Up of a Pfizer-BioNTech COVID-19 Vaccine-Induced Hemichorea-Hemiballismus; Insights Into Mechanisms of Basal Ganglia Dysfunction

Affiliations
Editorial

Clinical and Radiological Follow-Up of a Pfizer-BioNTech COVID-19 Vaccine-Induced Hemichorea-Hemiballismus; Insights Into Mechanisms of Basal Ganglia Dysfunction

Molly Cincotta et al. Tremor Other Hyperkinet Mov (N Y). .

Abstract

Asymmetric chorea unrelated to structural lesions is typically due to systemic etiologies, such as metabolic, autoimmune, or other inflammatory disorders. This is an editorial commenting on a paper by Batot C, Chea M, Zeidan S, et al. Clinical and radiological follow up of Pfizer-BioNTech COVID-19 vaccine-induced hemichorea-hemiballismus. Tremor and Other Hyperkinetic Movements; 2022; 12(1). DOI: https://doi.org/10.5334/tohm.688. A 90-year-old patient is reported who developed hemichorea shortly after his second vaccination against COVID-19. Hypometabolism was noted in the contralateral striatum. This case provides potential insights and raises questions about mechanisms of immune-mediated hemichorea.

Keywords: COVID-19; chorea; hemiballismus; hemichorea; vaccination.

PubMed Disclaimer

Conflict of interest statement

The authors have no competing interests to declare.

Comment on

References

    1. Batot C, Chea M, Zeidan S, et al. Clinical and radiological follow up of Pfizer-BioNTech COVID-19 vaccine-induced hemichorea-hemiballismus. Tremor and Other Hyperkinetic Movements. 2022; X(X). DOI: 10.5334/tohm.688 - DOI - PMC - PubMed
    1. Cincotta M, Walker RH. One Side of the Story; Clues to Etiology in Patients with Asymmetric Chorea. Tremor and Other Hyperkinetic Movements. 2022; 12(1): 3. DOI: 10.5334/tohm.675 - DOI - PMC - PubMed
    1. Ray STJ, Abdel-Mannan O, Sa M, et al. Neurological manifestations of SARS-CoV-2 infection in hospitalised children and adolescents in the UK: a prospective national cohort study. Lancet Child Adolesc Heal. 2021; 5(9): 631–641. DOI: 10.1016/S2352-4642(21)00193-0 - DOI - PMC - PubMed
    1. Brandão PRP, Grippe TC, Pereira DA, Munhoz RP, Cardoso F. New-Onset Movement Disorders Associated with COVID-19. Tremor and Other Hyperkinetic Movements. 2021; 11(1): 26. DOI: 10.5334/tohm.595 - DOI - PMC - PubMed
    1. Decio A, Balottin U, De Giorgis V, Veggiotti P. Acute chorea in a child receiving second dose of human papilloma virus vaccine. Pediatr Allergy Immunol. 2014; 25(3): 295–296. DOI: 10.1111/pai.12164 - DOI - PubMed