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Case Reports
. 2022 May 18:28:e01510.
doi: 10.1016/j.idcr.2022.e01510. eCollection 2022.

Outcomes of caspofungin use in the treatment of Candida-related urinary tract infections, a case series

Laila Rkieh  1 , Wasim S El Nekidy  2   3 , Leen Oyoun Alsoud  2 , Adnan Alatoom  2   4 , Rania El Lababidi  2 , Mohamad Mooty  2 , Ahmad R Nusair  5
Affiliations
Case Reports

Outcomes of caspofungin use in the treatment of Candida-related urinary tract infections, a case series

Laila Rkieh et al. IDCases. .

Abstract

Echinocandins are generally excluded in the treatment of Candida-related urinary tract infections due to their poor urinary concentration. In the presence of fluconazole resistant Candida species, such as C. Glabrata and C. auris, alternative therapies are needed. We herein report the use of caspofungin for the treatment of 10 patients with candiduria, including C. auris. Mycological cure was achieved in 6 of 7 patients and clinical cure was achieved in 8 of 10 patients. Larger studies are needed to confirm our findings.

Keywords: Candiduria; Caspofungin; Urinary tract infection.

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Conflict of interest statement

All authors declare no potential conflicts of interest include employment, consultancies, stock ownership, honoraria, paid expert testimony, patent applications/registrations, and grants or other funding.

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