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Editorial
. 2022 May 12:10:919426.
doi: 10.3389/fcell.2022.919426. eCollection 2022.

Editorial: Extracellular Vesicles as Next Generation Therapeutics

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Editorial

Editorial: Extracellular Vesicles as Next Generation Therapeutics

Sylwia Bobis-Wozowicz et al. Front Cell Dev Biol. .
No abstract available

Keywords: bioengineering; disease treatment; drug delivery; extracellular vesicles; nanomedicine; regeneration; therapy; vaccine.

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Conflict of interest statement

The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.

Figures

FIGURE 1
FIGURE 1
Characteristics, bioengineering and role of extracellular vesicles (EVs) in health and disease. EVs contain bioactive cargo in the form of proteins, lipids and nucleic acids which exert biological effects on target cells and thereby influence their fate. To improve functionality and specificity of EVs, they can be engineered by surface modification and/or loading a specific therapeutic cargo. Native and modified EVs can be used as next-generation cell-free therapeutics to improve health. On the contrary, EVs released in pathological conditions by, e.g. cancer cells or infected cells, participate in disease spreading and progression.

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  • Editorial on the Research Topic Extracellular Vesicles as Next Generation Therapeutics

References

    1. Wiklander O. P. B., Brennan M. Á., Lötvall J., Breakefield X. O., El Andaloussi S. (2019). Advances in Therapeutic Applications of Extracellular Vesicles. Sci. Transl. Med. 11, eaav8521. 10.1126/scitranslmed.aav8521 - DOI - PMC - PubMed
    1. Xu R., Rai A., Chen M., Suwakulsiri W., Greening D. W., Simpson R. J. (2018). Extracellular Vesicles in Cancer - Implications for Future Improvements in Cancer Care. Nat. Rev. Clin. Oncol. 15, 617–638. 10.1038/s41571-018-0036-9 - DOI - PubMed

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