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Case Reports
. 2022 Apr 26;10(12):3808-3813.
doi: 10.12998/wjcc.v10.i12.3808.

Acute pancreatitis-induced thrombotic thrombocytopenic purpura: A case report

Chun-Hua Wang  1 , Hai-Feng Jin  2 , Wen-Ge Liu  2 , Ying Guo  2 , Zhen Liu  2
Affiliations
Case Reports

Acute pancreatitis-induced thrombotic thrombocytopenic purpura: A case report

Chun-Hua Wang et al. World J Clin Cases. .

Abstract

Background: Thrombotic thrombocytopenic purpura (TTP) is a life-threatening but treatable disorder. Acute pancreatitis is a well-described consequence of TTP, but TTP as a consequence of acute pancreatitis is rare.

Case summary: A 32-year-old male developed acute pancreatitis due to a fatty diet and suffered splenectomy 3 years ago due to trauma. From day 4 of his onset of pain the blood examination showed the platelet extremely reduced, bilirubin elevated and creatinine increased. High clinical suspicion of TTP was made and prompt initiation of plasma exchange was given followed intravenous drip methylprednisolone. After 7 sessions of plasm exchange and the laboratory parameters were back to normal and the patient was discharged from the hospital on the 13th day of admission.

Conclusion: Patients develop acute pancreatitis with no apparent causes for hemolytic anemia and thrombocytopenia, the possibility of TTP should be considered. Treatments for TTP including plasm exchange should be evaluated as soon as a diagnosis is made.

Keywords: Acute pancreatitis; Case report; Glucocorticoid; Plasm exchange; Thrombotic thrombocytopenic purpura.

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Conflict of interest statement

Conflict-of-interest statement: No potential conflicts of interest relevant to this article were reported.

Figures

Figure 1
Figure 1
Abdominal computed tomography revealed signs of pancreatitis.
See this image and copyright information in PMC

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