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. 2022 Jun;63(6):830-832.
doi: 10.2967/jnumed.121.263694.

Tau Beats Amyloid in Predicting Brain Atrophy in Alzheimer Disease: Implications for Prognosis and Clinical Trials

Maura Malpetti  1   2 , Renaud La Joie  3 , Gil D Rabinovici  3   4
Affiliations

Tau Beats Amyloid in Predicting Brain Atrophy in Alzheimer Disease: Implications for Prognosis and Clinical Trials

Maura Malpetti et al. J Nucl Med. 2022 Jun.
No abstract available

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Figures

FIGURE 1.
FIGURE 1.
Single-subject amyloid and tau PET patterns at baseline and cortical atrophy over time. (Left and middle) 11C-Pittsburgh compound B (PIB) and 18F-flortaucipir (FTP) PET SUV ratio maps, respectively, with higher values indicate more severe pathology. (Right) Patterns derived from prospective longitudinal structural MRI scans after PET, with positive Jacobians indicating shrinkage over time. Patient 1 is 71-y-old with mild AD dementia; patient 2 is 61-y-old with mild AD dementia.
See this image and copyright information in PMC

References

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