Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 1986;27(3):378-87.
doi: 10.1186/BF03548152.

Morphologic evaluation of acute endometritis in mares with differing resistance to uterine infections

T Katila, T F Lock, R W Ely, A R Smith

Morphologic evaluation of acute endometritis in mares with differing resistance to uterine infections

T Katila et al. Acta Vet Scand. 1986.

Abstract
in English, German

The study was designed to determine differences between normal mares and mares with endometrial pathology in the inflammatory response after bacterial challenge. Six normal mares (biopsy category I) and 4 mares with pathological endometrial changes (biopsy category II) were given an intrauterine infusion of β-hemolytic streptococci on the second day of estrus. All mares had a similar kind of inflammatory response after the bacterial inoculation as assessed by rectal and vaginal examinations. There were no significant differences in the amount of discharge, uterine tone, uterine size and cervical relaxation between the groups. Leukocytic response, as determined by endometrial smears and biopsies, was of the same magnitude in both groups. Two mares from the pathological group were not able to eliminate the infection, but had vaginal discharge and bacteriologically positive uterine swabs until the end of the experiment. It is concluded that the inability of some mares to clear uterine infections cannot be explained by a deficient inflammatory response.

Föreliggande undersökning utfördes för att klargöra skillnaden mellan normala ston och ston med patologiska förändringar i endometriet beroende på en inflammatorisk reaktion ansluten till bakteriell infektion. Sex normala ston (biopsi kategori I) och 4 ston med patologiska förändringar i endometriet (biopsi kategori II) inokulerades intrauterint med β-hämoly tiska streptokocker under den andra brunstdagen. Alla ston uppvisaide en likadan inflammatorisk reaktion efter den bakteriella inokulationen, vilket konfirmerades vid rektala och va/ginala undersökningar. Inga signifikanta skillnader påvisades mellan de två grupperna visavis mängden av flytning, livmoderns tonus och storlek, samt avslapningen av cervix. Leukocytreaktionen, som bestämdes med hjälp av endometriella utstryk och biopsier, var av samma storleksgrad i båda grupperna. Två ston i den patologiska gruppen förmådde inte eliminera infektionen, utan hade vaginal flytning och bakteriologiskt positiva prov från livmodern ända till undersökningens slut. Vår slutsats är, att oförmåga att klara uterina infektioner inte kan förklaras bero på en bristande inflammatorisk reaktion.

PubMed Disclaimer

References

    1. Asbury A C, Halliivell REW, Foster GW, Longino SJ. Immunoglobulins in uterine secretions of mares with differing resistance to endometritis. Theriogenology. 1980;14:299–308. doi: 10.1016/0093-691X(80)90079-5. - DOI - PubMed
    1. Bowman T. Early response of the equine uterus to induced strep to- soccal endometritis. 1972.
    1. Greenhoff GR, Kenney RM. Evaluation of reproductive status of nonpregnant mares. J. Amer. vet. med. Ass. 1975;167:449–458. - PubMed
    1. Hughes JP, Loy RG. Proc. 15th Ann. Gonv. Amer. Ass. Equine Practnrs. 1969. Investigations on the effect of intrauterine inoculations of Streptococcus zooepidemicus in the mare; pp. 289–292.
    1. Kenney RM. Cyclic and pathologic changes of the mare endometrium as detected by biopsy, with a note on early embryonic death. J. Amer. vet. med. Ass. 1978;172:241–261. - PubMed

LinkOut - more resources