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. 2022 May 27;57(2):193-199.
doi: 10.1055/s-0041-1729936. eCollection 2022 Apr.

Periprosthetic Knee Infection - Part 2: Treatment

João Maurício Barretto  1 , André Luiz Siqueira Campos  2 , Nelson Hiroyuki Miyabe Ooka  3
Affiliations

Periprosthetic Knee Infection - Part 2: Treatment

João Maurício Barretto et al. Rev Bras Ortop (Sao Paulo). .

Abstract

Several treatment modalities are proposed for periprosthetic infections, with variable success rates. However, efficacy is related to the appropriate selection of cases for each type of treatment. Debridement with implant retention is indicated in acute infections with fixed implant, and its success depends on the type of infection, comorbidities of the host, and virulence of the etiological agent. One- or two-stage revision is required in cases in which biofilm is forming, or of implant loosening. The choice between performing the review in one or two stages depends on factors such as etiological agent identification, pathogen virulence, local and systemic host factors. Rescue procedures such as arthrodesis, amputation, resection arthroplasty or even antibiotic suppression are reserved for cases in which the infection has not been eradicated.

Keywords: antibiotic; arthroplasty, replacement, knee; surgical review; surgical site infection; treatment.

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Conflict of interest statement

Conflito de Interesses Os autores declaram não haver conflito de interesses. Dr. Barreto informa que recebeu honorários pessoais da Stryker Latin America, fora do presente trabalho.

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References

    1. Argenson J N, Arndt M, Babis G.Hip and Knee Section, Treatment, Debridement and Retention of Implant: Proceedings of International Consensus on Orthopedic Infections J Arthroplasty 201934(2S):S399–S419. - PubMed
    1. Infectious Diseases Society of America . Osmon D R, Berbari E F, Berendt A R. Diagnosis and management of prosthetic joint infection: clinical practice guidelines by the Infectious Diseases Society of America. Clin Infect Dis. 2013;56(01):e1–e25. - PubMed
    1. Parvizi J, Gehrke T. Anais do 2 o. Encontro do Consenso Internacional (ICM) em Infecção Musculoesqueletica [Internet] . ICM Philly 2019[citado 22 de março de 2020]. Disponível em:https://icmphilly.com/document/icm-document-translations/icm-document-po...
    1. Choo K J, Austin M, Parvizi J. Irrigation and Debridement, Modular Exchange, and Implant Retention for Acute Periprosthetic Infection After Total Knee Arthroplasty. JBJS Essential Surg Tech. 2019;9(04):e38. - PMC - PubMed
    1. Son W S, Shon O J, Lee D C, Park S J, Yang H S. Efficacy of Open Debridement and Polyethylene Exchange in Strictly Selected Patients with Infection after Total Knee Arthroplasty. Knee Surg Relat Res. 2017;29(03):172–179. - PMC - PubMed