Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2022 Summer;26(4):501-505.
doi: 10.5005/jp-journals-10071-24172.

Study of Clinicoradiological Profile in Posterior Reversible Encephalopathy Syndrome: An Experience from North India

Gourav Goyal  1 , Jitesh Jeswani  2
Affiliations

Study of Clinicoradiological Profile in Posterior Reversible Encephalopathy Syndrome: An Experience from North India

Gourav Goyal et al. Indian J Crit Care Med. 2022 Summer.

Abstract

Background: Posterior reversible encephalopathy syndrome (PRES) is a reversible condition. The Main pathological feature is vasogenic cerebral edema with predominant involvement of posterior part of the cerebrum. Clinical symptoms range from headache, seizure, and vision loss. We evaluated the clinicoradiological features of patients with PRES and their clinical outcome.

Materials and methods: A retrospective study with 30 cases from January 2014 to May 2017.

Results: Of thirty patients, 18 were females and twelve patients were male. The Mean age of the patients was 38.6 years. The most common presentation was seizure (66.6%) followed by altered mental status (53.3%) and headache (40%). The Main comorbid illnesses in our study were renal disease (36.7%), hypertension (23.3%), eclampsia, and postpartum sepsis (26.7%). The Most common site was the occipito-parietal region in the magnetic resonance imaging brain (66%). Atypical presentation involved the temporal lobe (16%), basal ganglia (6%), and microhemorrhage (6%). The Outcome was good with 20% mortalities.

Conclusion: PRES is a reversible condition and has a good outcome in most patients. In our study, seizure was the most common presentation and renal disease is the most common comorbid illness.

How to cite this article: Goyal G, Jeswani J. Study of Clinicoradiological Profile in Posterior Reversible Encephalopathy Syndrome: An Experience from North India. Indian J Crit Care Med 2022;26(4):501-505.

Keywords: Hypertension; Neuroimaging; Outcome; PRES.

PubMed Disclaimer

Conflict of interest statement

Source of support: Nil Conflict of interest: None

References

    1. Fugate JE, Claassen DO, Cloft HJ, Kallmes DF, Kozak OS, Rabinstein AA. Posterior reversible encephalopathy syndrome: associated clinical and radiologic findings. Mayo Clin Proc. 2010;85(5):427–432. doi: 10.4065/mcp.2009.0590. - DOI - PMC - PubMed
    1. Karuppannasamy D, Vikrant K, Raghuram A, Kumaar TM. Cortical visual loss in posterior reversible encephalopathy syndrome in late postpartum eclampsia: case series. Indian J Ophthalmol. 2014;62(5):635–638. doi: 10.4103/0301-4738.133525. - DOI - PMC - PubMed
    1. McKinney AM, Sarikaya B, Gustafson C, Truwit CL. Detection of microhemorrhage in posterior reversible encephalopathy syndrome using susceptibility-weighted imaging. AJNR Am J Neuroradiol. 2012;33(5):896–903. doi: 10.3174/ajnr.A2886. - DOI - PMC - PubMed
    1. Patil VC, Agrwal V, Rajput A, Garg R, Kshirsagar K, Chaudhari V. Clinical profile and outcome of posterior reversible encephalopathy syndrome (PRES). Ann Trop Med Public Health. 2015;8:105–112. doi: 10.4103/1755-6783.162354. - DOI
    1. Bansal S, Bansal R, Goyal MK, Takkar A, Singh R, Singh P, et al. Clinical, etiological and imaging profile of posterior reversible encephalopathy syndrome: a prospective and follow-up study. Ann Indian Acad Neurol. 2020;23(2):182–188. doi: 10.4103/aian.AIAN_379_18. - DOI - PMC - PubMed

LinkOut - more resources