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. 2022 May 17:9:905394.
doi: 10.3389/fsurg.2022.905394. eCollection 2022.

Efficacy and Safety of Prostatic Artery Embolization in the Treatment of High Risk Benign Prostatic Hyperplasia and its Influence on Postoperative Life Quality of Patients

Kun Wang  1 , Ming Chen  2 , Yiqing Liu  1 , Weiren Xiao  1 , Yonghong Qian  1 , Xu Liu  3
Affiliations

Efficacy and Safety of Prostatic Artery Embolization in the Treatment of High Risk Benign Prostatic Hyperplasia and its Influence on Postoperative Life Quality of Patients

Kun Wang et al. Front Surg. .

Abstract

Objective: To evaluate the efficacy, safety and postoperative quality of life of high risk benign prostatic hyperplasia (BPH) patients treated with prostatic artery embolization.

Methods: 34 patients with high-risk BPH were selectedfrom January 2020 to June 2021 in our hospital. All patients were treated with prostatic artery embolization. The changes of international prostate symptom score (IPSS), prostate volume (PV), remaining urine (RU), maximum urine flow rate (Qmax), quality of life scale -74(GQOLI-74), time to sleep without disturbance (HUS) judgment, self-rating anxiety scale (SAS) score and self-rating depression scale (SDS) were compared before operation, 1 month and 6 months after operation.

Results: Prostatic artery embolization was successful in all 34 patients, including unilateral embolization in 15 patients and bilateral embolization in 19 patients. No severe complications occurred in the postoperative patients. The IPSS, PV and RU levels of the patient one month and six months after surgery were lower than those before surgery, while the Qmax level was higher than that before surgery. Besides, the IPSS, PV and RU levels six months after surgery were significantly lower than those one month after surgery, and the Qmax level was significantly higher than that one month after surgery (p < 0.05). The GQOLI-74 score six months after surgery was significantly higher than that before surgery (p < 0.05). The HUS of the patient six months after surgery was significantly increased, and the SAS and SDS scores were significantly decreased as compared with those before surgery (p < 0.05).

Conclusion: For high-risk patients with BPH, prostate embolization is an effective and safe method, which can significantly improve the quality of life of patients after surgery and has good application prospects.

Keywords: benign prostatic hyperplasia; high risk; prostatic artery; prostatic artery embolization; quality of life.

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Conflict of interest statement

The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.

Figures

Figure 1
Figure 1
Changes in IPSS of patients before and after surgery.
Figure 2
Figure 2
Changes in PV of patients before and after surgery.
Figure 3
Figure 3
Changes in Qmax of patients before and after surgery.
Figure 4
Figure 4
Changes in RU of patients before and after surgery.
Figure 5
Figure 5
Changes in psychological function scores of patients before and after surgery.
Figure 6
Figure 6
Changes in social function scores of patients before and after surgery.
Figure 7
Figure 7
Changes in material life scores of patients before and after surgery.
Figure 8
Figure 8
Changes in body function scores of patients before and after surgery. Note: compared with before surgery, *p < 0.05. Note: compared with before operation, *p < 0.05; compared with one month after surgery, #p < 0.05.
Figure 9
Figure 9
Changes of HUS in patients before and after surgery.
Figure 10
Figure 10
Changes of SAS and SDS scores in patients before and after surgery. Note: compared with before surgery, *p < 0.05.
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