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. 2022 May;77(5-6):295-301.

[Chronic obstructive pulmonary disease. A chronic inflammatory disease]

[Article in French]
J L Corhay  1 , O Bonhomme  1 , V Heinen  1 , C Moermans  2 , R Louis  1
Affiliations
  • PMID: 35657186
Free article

[Chronic obstructive pulmonary disease. A chronic inflammatory disease]

[Article in French]
J L Corhay et al. Rev Med Liege. 2022 May.
Free article

Abstract
in English, French

Chronic Obstructive Pulmonary Disease (COPD) is a disease caused by a chronic inflammatory response induced by the inhalation of cigarette smoke or toxic particles/gases in the airways. However, we actually know that COPD is a disease that does not only induce inflammation in lung parenchyma and bronchi, but also provokes systemic inflammation which plays a role in multiple comorbidities. Thereby, treatment of COPD should not only focus on the bronchi to relieve symptoms, improve respiratory function and reduce the rate of exacerbations, but must also be extended to the systemic effects of the disease.

: La Broncho-Pneumopathie Chronique Obstructive (BPCO) est une maladie provoquée par une réponse inflammatoire chronique suite à l’inhalation de la fumée de cigarette ou d’aérocontaminants toxiques pour les voies aériennes. Cependant, nous savons aujourd’hui que la BPCO est une maladie induisant non seulement une inflammation au niveau du parenchyme pulmonaire et des bronches, mais aussi une inflammation systémique qui peut jouer un rôle dans de multiples comorbidités. Ainsi, le traitement de la BPCO ne doit pas seulement se focaliser sur le versant bronchique dans le but de soulager les symptômes, d’améliorer la fonction respiratoire et de réduire le taux d’exacerbation, mais doit aussi s’étendre aux effets systémiques de la maladie.

Keywords: Comorbidity; Inflammation; Treatment; COPD.

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