Immune gains through brain drains
- PMID: 35658011
- DOI: 10.1126/sciimmunol.add2045
Immune gains through brain drains
Abstract
In a mouse model of pneumococcal meningitis, skull channels provide extravascular signaling to the skull marrow capable of initiating local marrow hematopoiesis.
Comment on
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Cerebrospinal fluid can exit into the skull bone marrow and instruct cranial hematopoiesis in mice with bacterial meningitis.Nat Neurosci. 2022 May;25(5):567-576. doi: 10.1038/s41593-022-01060-2. Epub 2022 May 2. Nat Neurosci. 2022. PMID: 35501382 Free PMC article.
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