Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Comment
. 2022 Jun 2;29(6):873-875.
doi: 10.1016/j.stem.2022.05.002.

Expanding the precision oncology toolkit with micro-organospheres for early cancer diagnosis

J Jeya Vandana  1 , Lauretta A Lacko  2 , Shuibing Chen  3
Affiliations
Free article
Comment

Expanding the precision oncology toolkit with micro-organospheres for early cancer diagnosis

J Jeya Vandana et al. Cell Stem Cell. .
Free article

Abstract

Using an automatic microfluidics droplet platform, Ding et al. successfully replicated the tumor micro-environment by generating micro-organospheres, which were then used to predict the response to anti-tumor drugs. These miniature models could be obtained within an extremely short time frame of 14 days, amplifying their role in facilitating cancer treatment decisions.

PubMed Disclaimer

Conflict of interest statement

Declaration of interests S.C. is the co-founder of OncoBeat, LLC and a member of the Scientific Advisory Board of Cell Stem Cell.

Comment on

  • Patient-derived micro-organospheres enable clinical precision oncology.
    Ding S, Hsu C, Wang Z, Natesh NR, Millen R, Negrete M, Giroux N, Rivera GO, Dohlman A, Bose S, Rotstein T, Spiller K, Yeung A, Sun Z, Jiang C, Xi R, Wilkin B, Randon PM, Williamson I, Nelson DA, Delubac D, Oh S, Rupprecht G, Isaacs J, Jia J, Chen C, Shen JP, Kopetz S, McCall S, Smith A, Gjorevski N, Walz AC, Antonia S, Marrer-Berger E, Clevers H, Hsu D, Shen X. Ding S, et al. Cell Stem Cell. 2022 Jun 2;29(6):905-917.e6. doi: 10.1016/j.stem.2022.04.006. Epub 2022 May 3. Cell Stem Cell. 2022. PMID: 35508177 Free PMC article.

LinkOut - more resources