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. 2022 Sep;38(9):885-888.
doi: 10.1016/j.tig.2022.05.003. Epub 2022 May 31.

Are phenome-wide association studies feasible in a developing country?

Gerard G Dumancas  1 , Destiny Harrison  2 , Jonathan Adam Rico  3 , Pia Regina Fatima C Zamora  3 , Aretha G Liwag  4 , Joselito F Villaruz  4 , Ma Luz Vicenta V Guanzon  5 , Hans Francis D Ferraris  5 , Patrick Joseph B Jalandoni  6 , Webster F Padernal  6 , Bea Nestie L Villareal  6 , Ria A Maculada  6 , Rachael Mae A Fernandez  6 , Felix Ray Villa  6 , Romulo de Castro  7
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Are phenome-wide association studies feasible in a developing country?

Gerard G Dumancas et al. Trends Genet. 2022 Sep.

Abstract

Phenome-wide association studies (PheWASs), a powerful approach that examines phenotypes associated with a genetic marker, have been used extensively in highly developed countries. Although there may be a clear need for PheWAS in a developing country such as the Philippines, limitations related to resources and practicality would make conducting them a challenge.

Keywords: PheWAS; Philippines; feasibility; genotype; phenome-wide association study.

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Declaration of interests The authors declare that they have no conflict of interest.

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